Nontypeable Haemophilus influenzae Otitis Media: Mastoiditis and Meningitis Complicated with Central Venous Thrombosis in an Immunocompetent Child

• Published in: Case reports in infectious diseases Vol. 2021; pp. 8845200 - 5
• Main Authors: Gönüllü, Erdem, Özkan, Nesrin, Soysal, Ahmet, Acıoğlu, Engin, Tavil, Emine Betül, Ötgün, Selin Nar, Karaböcüoğlu, Metin
• Format: Journal Article
• Language: English
• Published: Egypt Hindawi 2021; Hindawi Limited; Wiley
• Subjects: Antibiotics; Blood clots; Case Report; Case reports; Children & youth; Ear diseases; Fever; Health care; Immunocompetence; Influenza; Medical imaging; Meningitis; Mutation; Pathogens; Pediatrics; Proteins; Sinuses; Streptococcus infections; Thrombosis; Vaccines; Turkey
• ISSN: 2090-6625; 2090-6633
• DOI: 10.1155/2021/8845200

Implementation of the Haemophilus influenzae type B (Hib) conjugate vaccine brought about a reduction in the number of cases and morbidity from type B but an increase in nontypeable strain infections. Nontypeable Haemophilus influenzae (NTHi) commonly colonizes children’s upper respiratory tract and causes otitis media, sinusitis, and bronchitis. Invasive NTHi diseases, such as meningitis and septicemia, have rarely been reported. Herein, we discuss a previously healthy, fully immunized 3-year-old girl presented with otitis media and mastoiditis leading to meningitis caused by NTHi complicated with central venous thrombosis. She was treated with antibiotics, mastoidectomy and ventilation tube insertion, and anticoagulation therapy and recovered uneventfully. Through this case, we wish to share our unique clinical experience that NTHi should be born in mind as a potential pathogen that can cause meningitis in previously healthy children, which may be helpful in future cases.