Diagnostic Potential of 3D-Data–Based Reconstruction Software: An Analysis of the Rare Disease Pattern of Cherubism

Cherubism is an autosomal-dominant syndrome characterized by bilateral maxillomandibular bony degeneration, fibrous connective tissue hyperplasia, and displacement of permanent tooth germs. Reossification of the cystic lumen occurs spontaneously, but dislocated teeth must be realigned orthodonticall...

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Published inThe Cleft palate-craniofacial journal Vol. 46; no. 2; pp. 215 - 219
Main Authors Holst, Alexandra Ioana, Hirschfelder, Ursula, Holst, Stefan
Format Journal Article
LanguageEnglish
Published Los Angeles, CA SAGE Publications 01.03.2009
American Cleft Palate-Craniofacial Association
SAGE PUBLICATIONS, INC
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Abstract Cherubism is an autosomal-dominant syndrome characterized by bilateral maxillomandibular bony degeneration, fibrous connective tissue hyperplasia, and displacement of permanent tooth germs. Reossification of the cystic lumen occurs spontaneously, but dislocated teeth must be realigned orthodontically. Advancements in virtual 3D reconstruction of anatomic structures based on computed tomography (CT) or cone beam CT data have provided for more predictable individual treatment planning. We evaluated two software programs for making densitometry and volume measurements of cystic areas in the mandibles, and for 3D visualization of permanent tooth germs within the cystic lumen, in two siblings with cherubism.
AbstractList Cherubism is an autosomal-dominant syndrome characterized by bilateral maxillomandibular bony degeneration, fibrous connective tissue hyperplasia, and displacement of permanent tooth germs. Reossification of the cystic lumen occurs spontaneously, but dislocated teeth must be realigned orthodontically. Advancements in virtual 3D reconstruction of anatomic structures based on computed tomography (CT) or cone beam CT data have provided for more predictable individual treatment planning. We evaluated two software programs for making densitometry and volume measurements of cystic areas in the mandibles, and for 3D visualization of permanent tooth germs within the cystic lumen, in two siblings with cherubism.
Author Holst, Alexandra Ioana
Holst, Stefan
Hirschfelder, Ursula
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Keywords computed tomography
treatment planning
cherubism
orthodontics
three-dimensional reconstruction
Radiodiagnosis
Cherubism
Stomatology
Diseases of the osteoarticular system
Anatomical reconstruction
Orthodontic procedures
Treatment
Surgery
Rare disease
Medical imagery
Software
Computerized axial tomography
Diagnosis
Osteochondrodysplasia
Treatment planning
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Snippet Cherubism is an autosomal-dominant syndrome characterized by bilateral maxillomandibular bony degeneration, fibrous connective tissue hyperplasia, and...
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SubjectTerms Absorptiometry, Photon
Bacteria
Biological and medical sciences
Bone Density
Cherubism - diagnostic imaging
Cherubism - genetics
Child
Cone-Beam Computed Tomography - methods
Dentistry
Diseases of the osteoarticular system
Female
Humans
Image Processing, Computer-Assisted - methods
Imaging, Three-Dimensional - methods
Male
Malformations and congenital and or hereditary diseases involving bones. Joint deformations
Mandible - diagnostic imaging
Medical sciences
Otorhinolaryngology. Stomatology
Patient Care Planning
Software
Studies
Teeth
Three dimensional imaging
Tomography, X-Ray Computed - methods
Tooth Germ - diagnostic imaging
User-Computer Interface
Title Diagnostic Potential of 3D-Data–Based Reconstruction Software: An Analysis of the Rare Disease Pattern of Cherubism
URI https://journals.sagepub.com/doi/full/10.1597/07-015.1
https://www.ncbi.nlm.nih.gov/pubmed/19254051
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