Construction of a self–reporting molecularly–imprinted electrochemical sensor based on CuHCF modified by rGNR–rGO for the detection of zearalenone

• Published in: Food chemistry Vol. 448; p. 139154
• Main Authors: Zhou, Binbin, Xie, Hao, Li, Xinyi, Zhu, Yongbo, Huang, Lijun, Zhong, Ming, Chen, Liang
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.08.2024
• Subjects: Copper - chemistry; Copper hexacyanoferrate; Electrochemical Techniques - instrumentation; Electrodes; Ferrocyanides - chemistry; Food Contamination - analysis; Graphite - chemistry; Limit of Detection; Molecular Imprinting; Molecularly–imprinted electrochemical sensor; Reduced graphene nanoribbons; Reduced graphene oxide; Self–reporting; Zearalenone; Zearalenone - analysis; Copper hexacyanoferrate; Zearalenone; Molecularly–imprinted electrochemical sensor; Reduced graphene nanoribbons; Reduced graphene oxide; Self–reporting
• ISSN: 0308-8146; 1873-7072
• DOI: 10.1016/j.foodchem.2024.139154

A self–reporting molecularly–imprinted electrochemical sensor is prepared for the detection of Zearalenone (ZEA). Firstly, the reduced graphene nanoribbons and reduced graphene oxide (rGNR–rGO) were simultaneously modified onto a glassy carbon electrode (GCE) to improve the sensor's sensitivity. After electrodepositing copper nanoparticles onto the rGNR–rGO/GCE, cyclic voltammetry scanning was performed in potassium ferrocyanide solution, and copper hexacyanoferrate (CuHCF) was deposited onto rGNR–rGO/GCE to further improve the sensor's sensitivity while giving it self–reporting capability. Then, molecularly–imprinted polymer films were prepared on the CuHCF/rGNR–rGO/GCE to ensure the selectivity of the sensor. It is found that the linear range of ZEA detection by the constructed sensor is 0.25–500 ng·mL −1, with a detection limit of 0.09 ng·mL −1. This sensor shows the merits of good selectivity, high sensitivity and accurate detection, providing a great possibility for the precise detection of low concentration ZEA in food. [Display omitted] •rGNR–rGO were co-modified onto GCE to improve the sensitivity of the sensor.•CuHCF was formed in [Fe(CN)6]3−/4– solution by CV scanning CuNPs/rGNR–rGO/GCE.•CuHCF can increase sensitivity while giving the sensor self-reporting capability.•MIP is generated on the electrode by electropolymerization to improve selectivity.•The sensor has a linear range of 0.25–500 ng/mL and a detection limit of 0.09 ng/mL.