Late Lung Metastasis in a Patient with a Clear Cell Chondrosarcoma: An Indication for a Life-Long Follow-Up?

Background. Clear cell chondrosarcoma (CCCS) is a rare subtype of chondrosarcoma and comprises between 1.6% and 2.5% of all chondrosarcoma. They are known to be chemo- and radiotherapy resistant; surgical resection is therefore the therapy of choice. Methods. We present a 63-year-old woman with a pr...

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Published inCase reports in oncological medicine Vol. 2021; pp. 7205649 - 8
Main Authors West, Paulien, Jacobs, Celine, Saerens, Michael, Creytens, David, Sys, Gwen, Lapeire, Lore
Format Journal Article
LanguageEnglish
Published United States Hindawi 02.12.2021
Hindawi Limited
Wiley
Subjects
Amputation
Biopsy
Bone cancer
Bones
Case Report
Case reports
Lung cancer
Medical imaging
Metastasis
Orthopedics
Patients
Radiation therapy
Sarcoma
Surgeons
Surgery
Tumors
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Summary:Background. Clear cell chondrosarcoma (CCCS) is a rare subtype of chondrosarcoma and comprises between 1.6% and 2.5% of all chondrosarcoma. They are known to be chemo- and radiotherapy resistant; surgical resection is therefore the therapy of choice. Methods. We present a 63-year-old woman with a progressive lung nodule 20 years after initial diagnosis and treatment of a clear cell chondrosarcoma of the right os naviculare. Results. On serial CT scans of the chest, an asymptomatic, slowly growing nodule in the left upper lung lobe was detected. CT-guided transthoracic biopsy of this nodule confirmed the diagnosis of a chondrosarcoma lung metastasis. Video-assisted thoracoscopic wedge resection was performed with complete removal of the nodule. The patient recovered well from surgery and remains in good health during further follow-up. Conclusion. Given the tendency of clear cell chondrosarcoma to recur and metastasize after extended periods of time, a long-term, possibly life-long follow-up and clinical surveillance is advisable in these patients.
Bibliography:Academic Editor: Ossama W. Tawfik
ISSN:2090-6706
2090-6714
DOI:10.1155/2021/7205649