Carbon dots and chitosan composite film based biosensor for the sensitive and selective determination of dopamine

• Published in: Analyst (London) Vol. 138; no. 18; pp. 5417 - 5423
• Main Authors: Huang, Qitong, Hu, Shirong, Zhang, Hanqiang, Chen, Jianhua, He, Yasan, Li, Feiming, Weng, Wen, Ni, Jiancong, Bao, Xiuxiu, Lin, Yi
• Format: Journal Article
• Language: English
• Published: England 21.09.2013
• Subjects: Biosensing Techniques - methods; Buffers; Carbon - chemistry; Chitosan - chemistry; Diffusion; Dopamine - analysis; Dopamine - chemistry; Electrochemistry; Electrodes; Hydrogen-Ion Concentration; Limit of Detection; Nanocomposites - chemistry; Oxidation-Reduction
• ISSN: 0003-2654; 1364-5528; 1364-5528
• DOI: 10.1039/c3an00510k

A simple, sensitive and reliable dopamine (DA) biosensor was developed based on a carbon dots (CDs) and chitosan (CS) composite film modified glassy carbon electrode (CDs-CS/GCE). Under optimal conditions, the CDs-CS/GCE showed a better electrochemical response for the detection of DA than that of the glassy carbon electrode (GCE). The oxidation peak current ( I pa ) of DA was linear with the concentration of DA in the range from 0.1 μM to 30.0 μM with the limit of detection as 11.2 nM (3 S / N ). The CDs-CS/GCE was applied to the detection of DA content in an injection solution of DA with satisfactory results. A simple, sensitive and reliable dopamine (DA) biosensor was developed based on a carbon dots (CDs) and chitosan (CS) composite film modified glassy carbon electrode (CDs-CS/GCE).