Unravelling the labyrinth of palladium-catalysed reactions involving isocyanides

Isocyanides possess a rich history in the world of synthetic chemistry. Recently the scope of this already versatile class of reagent has been expanded into its use in palladium-catalysed cascade sequences. The scope of this type of reaction is explored in depth and this tutorial review focuses on i...

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Bibliographic Details
Published inChemical Society reviews Vol. 42; no. 12; pp. 4867 - 488
Main Author Lang, Stuart
Format Journal Article
LanguageEnglish
Published England 21.06.2013
Subjects
Cascades
Chemical reactions
Labyrinth
Strategy
Synthesis (chemistry)
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Summary:Isocyanides possess a rich history in the world of synthetic chemistry. Recently the scope of this already versatile class of reagent has been expanded into its use in palladium-catalysed cascade sequences. The scope of this type of reaction is explored in depth and this tutorial review focuses on its various applications in chemical synthesis, and the wide range of systems that can be efficiently prepared using this strategy are documented. Isocyanides possess a rich history in the world of synthetic chemistry. Recently the scope of this already versatile class of reagent has been expanded into its use in palladium-catalysed cascade sequences. The scope of this type of reaction is explored in depth and this tutorial review focuses on its various applications in chemical synthesis.
Bibliography:Stuart Lang was born in Paisley in 1978 and was educated at the University of Strathclyde (MSci 2001 and PhD 2005). After a fellowship at the University of York he worked for Astrazeneca (Charnwood) in their medicinal chemistry department before returning to the University of Strathclyde. His research interests are in the development and understanding of synthetic methodology that can be used for the synthesis of biologically active molecules and chemical materials.
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ISSN:0306-0012
1460-4744
DOI:10.1039/c3cs60022j