Hashimoto's thyroiditis-induced cryptogenic organizing pneumonia: A case report

A 49-year-old female patient developed chest tightness and shortness of breath without apparent cause and presented to a local hospital. Chest radiography indicated increased thickening of the lung texture, increased multiple patchy densities in the lower lobes of the bilateral lungs and a slightly...

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Bibliographic Details
Published inExperimental and therapeutic medicine Vol. 18; no. 6; pp. 4609 - 4616
Main Authors Guo, Litao, Chen, Bo, Zhang, Lei, Deng, Yuan, Li, Hao, Shi, Qin Dong
Format Journal Article
LanguageEnglish
Published Greece Spandidos Publications 01.12.2019
Spandidos Publications UK Ltd
D.A. Spandidos
Subjects
Antibiotics
Biopsy
Blood
Body temperature
Bronchiolitis
Bronchoscopy
Care and treatment
Case reports
CAT scans
Chest x-rays
Corticosteroid drugs
Diagnostic imaging
Glucocorticoids
Health aspects
Hemoglobin
Imipenem
Infection
Infections
Laboratories
Lung diseases
Lungs
Meropenem
Patients
Pneumonia
Proteins
Radiography
Respiratory tract diseases
Thyroid cancer
Thyroid diseases
Thyroid gland
Thyroiditis
Tumors
Ventilators
Viral infections
cryptogenic organizing pneumonia
bronchiolitis obliterans with organizing pneumonia
Hashimoto's thyroiditis
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Summary:A 49-year-old female patient developed chest tightness and shortness of breath without apparent cause and presented to a local hospital. Chest radiography indicated increased thickening of the lung texture, increased multiple patchy densities in the lower lobes of the bilateral lungs and a slightly enlarged thyroid. The patient was treated for pulmonary infection with antibiotics but the symptoms persisted. A repeated CT scan revealed ground-glass attenuation of the bilateral lungs with multiple flaky exudates and visible bronchogenic signs. The symptoms did not improve after broadening anti-microbial coverage. Bronchoscopy and biopsy confirmed cryptogenic organizing pneumonia (COP). Thyroid ultrasound and thyroid function tests jointly confirmed the diagnosis of Hashimoto's thyroiditis (HT). After receiving corticosteroid treatment, the patient's condition improved and she was discharged. This case demonstrates that COP may present in combination with Hashimoto's thyroiditis (HT) and may possibly even be caused by HT. Early confirmation of diagnosis and treatment will help to improve the prognosis of such patients.
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ISSN:1792-0981
1792-1015
DOI:10.3892/etm.2019.8143