Synthesis, Characterization and Antifungal Activity of Metal Complexes of 2-(5-((2-Chlorophenyl)Diazenyl)-2-Hydroxybenzylidene) Hydrazinecarbothioamide

• Published in: Phosphorus, sulfur, and silicon and the related elements Vol. 187; no. 11; pp. 1312 - 1323
• Main Authors: El-Tabl, Abdou S., Shakdofa, Mohamad M. E., El-Seidy, Ahmed M. A., Al-Hakimi, Ahmed N.
• Format: Journal Article
• Language: English
• Published: ABINGDON Taylor & Francis Group 01.11.2012; Taylor & Francis; Taylor & Francis Ltd
• Subjects: Antifungal activity; azo-dye; Chemistry; Chemistry, Inorganic & Nuclear; Chemistry, Organic; complexes; Internet; Ligands; Metals; Phosphorus; Physical Sciences; Schiff base; Science & Technology; Silicon; spectroscopic studies; Sulfur; synthesis; Thiosemicabazone; synthesis; azo-dye; CRYSTAL-STRUCTURE; MACROCYCLIC LIGAND; COBALT(II); NICKEL(II) COMPLEXES; CU(II) COMPLEXES; Thiosemicabazone; Schiff base; COPPER(II) COMPLEXES; BIOLOGICAL-ACTIVITY; HYDRAZONE LIGAND; spectroscopic studies; SCHIFF-BASE LIGANDS; DERIVATIVES; complexes
• ISSN: 1042-6507; 1563-5325
• DOI: 10.1080/10426507.2012.657310

New metal complexes of Co(II), Cu(II), Ni(II), Zn(II), Mn(II), Fe(III), Ru(III), UO 2 (II), and VO(II) with the Schiff base, 2-(5-((2-chlorophenyl)diazenyl)-2-hydroxy- benzylidene) hydrazine-carbothioamide (H 2 L) have been prepared and characterized by elemental and thermal analyses, FT-IR, UV-Vis, mass spectra, 1 H-NMR, and ESR as well as conductivity and magnetic moments measurements. The IR spectra showed that the ligand acts as neutral tridentate, neutral bidentate or monobasic tridentate ligand. The geometries of metal complexes were either octahedral or square pyramidal. The ESR spectra of the solid copper(II) complexes indicated an axial symmetry type of a d (x2-y2) ground state with considerably ionic or covalent environment. The effect of the presence of an azo group on the biological activity of the ligand was investigated. The ligand and its complexes are biologically inactive due to the presence of azo group. Supplemental materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the related elements to view the free supplemental file.