Stretchable, flexible and breathable polylactic acid/polyvinyl pyrrolidone bandage based on Kirigami for wounds monitoring and treatment

Chronic wounds are slow to recover. During treatment, the dressing needs to be removed to check the recovery status, a process that often results in wound tears. Traditional dressings lack stretching and flexing properties and are not suitable using on wounds in joints, which require movement from t...

Full description

Saved in:
Bibliographic Details
Published inInternational journal of biological macromolecules Vol. 237; p. 124204
Main Authors Xu, Lei, Ding, Liqiang, Sun, Yuehua, Zhang, Tong, Zhu, Youfu, Yan, Bingyu, Yang, Min, Ramakrishna, Seeram, Zhang, Jun, Long, Yun-Ze
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 15.05.2023
Subjects
Bandages
Photothermal therapy
Polyesters
Polyvinyls
Povidone
Smart wound dressing
Wound infection monitoring
Photothermal therapy
Wound infection monitoring
Smart wound dressing
Online AccessGet full text

Cover

More Information
Summary:Chronic wounds are slow to recover. During treatment, the dressing needs to be removed to check the recovery status, a process that often results in wound tears. Traditional dressings lack stretching and flexing properties and are not suitable using on wounds in joints, which require movement from time to time. In this study, we present a stretchable, flexible and breathable bandage consisting of three layers, including Mxene coating on the top, the polylactic acid/polyvinyl pyrrolidone (PLA/PVP) layer designed as Kirigami in the middle, and the f-sensor at the bottom. By the way, the f-sensor is in contact with the wound sensing real-time microenvironmental changes due to infection. When the infection intensifies, the Mxene coating at the top is utilized to enable anti-infection treatment. And Kirigami structure of PLA/PVP ensures that this bandage has stretchability, bendability, and breathability. The stretch of the smart bandage increases to 831 % compared to the original structure, and the modulus reduces to 0.04 %, which adapts extremely well to the movement of the joints and relieves the pressure on the wound. This monitoring-treatment closed-loop working mode, eliminating the need to remove dressings and avoid tissue tearing, shows a promising capability in the field of surgical wound care.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0141-8130
1879-0003
DOI:10.1016/j.ijbiomac.2023.124204