Circulating levels of the terminal complement complex are associated with hypercoagulability in patients with stable coronary artery disease

•Complement and coagulation activation coincide in coronary artery disease (CAD).•In CAD, complement activation coincides with endothelial activation and damage.•In CAD, complement activation does not coincide with platelet activation.•A novel link between immunity and hemostasis in CAD is demonstra...

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Published inThrombosis research Vol. 196; pp. 106 - 108
Main Authors Kluge, Karsten E., Langseth, Miriam S., Bratseth, Vibeke, Pettersen, Alf Å., Arnesen, Harald, Tønnessen, Theis, Seljeflot, Ingebjørg, Helseth, Ragnhild
Format Journal Article
LanguageEnglish
Published United States Elsevier Ltd 01.12.2020
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Summary:•Complement and coagulation activation coincide in coronary artery disease (CAD).•In CAD, complement activation coincides with endothelial activation and damage.•In CAD, complement activation does not coincide with platelet activation.•A novel link between immunity and hemostasis in CAD is demonstrated.
Bibliography:SourceType-Other Sources-1
ObjectType-Article-2
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ObjectType-Correspondence-1
ISSN:0049-3848
1879-2472
DOI:10.1016/j.thromres.2020.08.023