High-Power Ultrasonic Transducer for Effective Hemolysis

To realize compact and portable hemolysis devices, an ultrasonic transducer with a blood channel is proposed in this study. Ultrasound waves are focused by a parabolic reflector to generate high sound pressure inside the channel for hemolysis. The hemolysis performance of the transducer is evaluated...

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Published inIEEE transactions on ultrasonics, ferroelectrics, and frequency control Vol. 69; no. 1; pp. 181 - 186
Main Authors Wu, Xiaogang, Chen, Kang, Hoshijima, Yasushi, Hariu, Taro, Yamazaki, Hiroki, Miyake, Susumu, Morita, Takeshi
Format Journal Article
LanguageEnglish
Published United States IEEE 01.01.2022
The Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subjects
Acoustic pressure
Acoustics
Blood
Cells (biology)
Electron tubes
Flow velocity
Hemolysis
high-power ultrasonic transducer
Humans
medical ultrasound
parabolic focusing
Parabolic reflectors
Portable equipment
Sound
Sound pressure
Transducers
Ultrasonic imaging
Ultrasonic transducers
Ultrasonic variables measurement
Ultrasonics
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Summary:To realize compact and portable hemolysis devices, an ultrasonic transducer with a blood channel is proposed in this study. Ultrasound waves are focused by a parabolic reflector to generate high sound pressure inside the channel for hemolysis. The hemolysis performance of the transducer is evaluated using simulations and experiments. Experiments are performed with various voltages and flow rates to verify the feasibility of hemolysis. The hemolysis rate is more than 93% at an applied voltage of 80 Vp-p, a flow rate of 0.25 mL/min, and a driving frequency of 1.28 MHz.
Bibliography:ObjectType-Article-1
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ISSN:0885-3010
1525-8955
DOI:10.1109/TUFFC.2021.3116977