Cytotoxic 5-Hydroxyindole Alkaloids from the Marine Sponge Scalarispongia sp

• Published in: Journal of heterocyclic chemistry Vol. 50; no. 6; pp. 1400 - 1404
• Main Authors: Lee, Yeon-Ju, Lee, Dong-Geun, Rho, Hyun Soo, Krasokhin, Vladimir B., Shin, Hee Jae, Lee, Jong Seok, Lee, Hyi-Seung
• Format: Journal Article
• Language: English
• Published: HOBOKEN Blackwell Publishing Ltd 01.11.2013; Wiley; Wiley Subscription Services, Inc
• Subjects: Chemistry; Chemistry, Organic; Marine; Physical Sciences; Scalarispongia; Science & Technology; HYRTIOS; DRUG LEADS; SPONGOSORITES SP; NATURAL-PRODUCTS; A-C; BISINDOLE ALKALOIDS; ANNELATED INDOLE SERIES; INHIBITORS; BIS; DERIVATIVES

Three new 5‐hydroxyindole alkaloids (1, 2, 3) along with seven known analogs (4, 5, 6, 7, 8, 9, 10) were isolated from a Dokdo marine sponge Scalarispongia sp. The elucidation of the structures of the new compounds by spectroscopic analyses indicated that these compounds were an indole glyoxylate (1...