Orchestrating the unfolded protein response in health and disease

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Bibliographic Details
Published inThe Journal of clinical investigation Vol. 110; no. 10; pp. 1389 - 1398
Main Author Kaufman, Randal J
Format Journal Article
LanguageEnglish
Published United States American Society for Clinical Investigation 01.11.2002
Subjects
Activating Transcription Factor 6
Apoptosis
Biomedical research
Diabetes Mellitus - genetics
Diabetes Mellitus - metabolism
DNA-Binding Proteins - metabolism
eIF-2 Kinase - metabolism
Endoplasmic reticulum
Endoplasmic Reticulum - metabolism
Endoribonucleases
Energy
Enzyme Activation
Genetic Diseases, Inborn - genetics
Genetic Diseases, Inborn - metabolism
Glucose
Glucose - metabolism
Humans
Hyperhomocysteinemia - genetics
Hyperhomocysteinemia - metabolism
Ischemia - metabolism
Kinases
Membrane Proteins
Metabolism
Models, Biological
Neoplasms - genetics
Neoplasms - metabolism
Organelles - metabolism
Physiology
Protein Folding
Protein Serine-Threonine Kinases - genetics
Protein Serine-Threonine Kinases - metabolism
RNA Splicing
Signal Transduction
Stress, Physiological - genetics
Stress, Physiological - metabolism
Transcription Factors - metabolism
Virus Diseases - etiology
Virus Diseases - metabolism
Yeast
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Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:0021-9738
1558-8238
DOI:10.1172/jci0216886