The Origin of Dual‐Emission in PLICT Compounds – an Empirical Approach

• Published in: Chemistry : a European journal Vol. 30; no. 18; pp. e202304143 - n/a
• Main Authors: Scheller, Zoe Nonie, Liese, David, Siera, Hannah, Semleit, Nina, Schmiedtchen, Marco, Wölper, Christoph, Haberhauer, Gebhard
• Format: Journal Article
• Language: English
• Published: Germany Wiley Subscription Services, Inc 25.03.2024
• Subjects: Charge transfer; Chemical compounds; DFT calculations; Emitters; excited states; Fluorescence; Fluorescence spectroscopy; Fluorescent indicators; Fluorophores; Multiplexing; PLICT states; Scientific research; Viscosity; excited states; fluorescence; DFT calculations; PLICT states
• ISSN: 0947-6539; 1521-3765
• DOI: 10.1002/chem.202304143

Fluorescence spectroscopy proves to be a powerful and versatile tool in scientific research, demanding ongoing advancements of fluorescence probes to cater to a broad range of applications. The particular interest lies in the development of fluorophores with multiplexing capability, emitting from more than one excited state depending on the polarity and viscosity of the surrounding medium. Here, we present a variety of novel dual planarized intramolecular charge transfer (PLICT) emitters based on cyano‐1‐aminoindole structures. We have chosen a combination of experimental studies, theoretical calculations and the creation of a unique fluorophore cataloging map. This map serves as a useful tool for empirically determining the origin of both fluorescence bands. Dual‐emitting PLICT compounds based on cyano‐1‐aminoindole structures and exploration of their fluorescence behavior are presented. Combination of experimental studies, theoretical calculations, and a unique fluorophore cataloging map allows for the easy determination of the origin of fluorescence bands.