Release of prostaglandins after amniotomy is not mediated by oxytocin

The rise in peripheral plasma levels of 13,14-dihydro-15-keto-prostaglandin F (PGFM) following amniotomy has now been shown to be maximal within five minutes of the procedure, and levels remain elevated for at least 30 minutes. There was no change in plasma oxytocin levels with amniotomy and therefo...

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Published inBritish journal of obstetrics and gynaecology Vol. 87; no. 1; p. 43
Main Authors Sellers, S M, Hodgson, H T, Mitchell, M D, Anderson, A B, Turnbull, A C
Format Journal Article
LanguageEnglish
Published England 01.01.1980
Subjects
Female
Humans
Labor, Induced
Oxytocin - blood
Oxytocin - physiology
Pregnancy
Prostaglandins F - blood
Prostaglandins F - metabolism
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Summary:The rise in peripheral plasma levels of 13,14-dihydro-15-keto-prostaglandin F (PGFM) following amniotomy has now been shown to be maximal within five minutes of the procedure, and levels remain elevated for at least 30 minutes. There was no change in plasma oxytocin levels with amniotomy and therefore a local mechanism for prostaglandin release has been postulated.
ISSN:0306-5456
DOI:10.1111/j.1471-0528.1980.tb04424.x