Acute Fulminant Colitis Caused by Idiopathic Mesenteric Inflammatory Veno-Occlusive Disease

Mesenteric inflammatory veno-occlusive disease (MIVOD) is an uncommon but important cause of bowel inflammation. MIVOD is characterised by lymphocytic inflammation and non-thrombotic occlusion of the mesenteric venules and veins. We present the case of a young man who presented with acute fulminant...

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Bibliographic Details
Published inCase reports in gastroenterology Vol. 1; no. 1; pp. 152 - 156
Main Authors Canavan, James B., Coss, Alan, Leader, Mary, Patchett, Stephen E.
Format Journal Article
LanguageEnglish
Published Basel, Switzerland S. Karger AG 13.12.2007
Karger Publishers
Subjects
Colectomy
Ischemic colitis
Mesenteric inflammatory veno-occlusive disease
Mesenteric vascular occlusion
Necrosis
Published: December 2007
Mesenteric inflammatory veno-occlusive disease
Mesenteric vascular occlusion
Colectomy
Ischemic colitis
Necrosis
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Summary:Mesenteric inflammatory veno-occlusive disease (MIVOD) is an uncommon but important cause of bowel inflammation. MIVOD is characterised by lymphocytic inflammation and non-thrombotic occlusion of the mesenteric venules and veins. We present the case of a young man who presented with acute fulminant colitis, requiring colectomy. The differential diagnosis, pathogenesis and treatment are discussed. This case illustrates the rapid progression from ‘well’ to ‘colectomy’ that can occur with MIVOD. MIVOD should be considered in the differential diagnosis of colitis that does not respond to conventional medical treatment.
ISSN:1662-0631
1662-0631
DOI:10.1159/000112222