Ataxic form of central pontine myelinolysis

Central pontine myelinolysis (CPM), a neurologic disorder caused most frequently by rapid correction of hyponatremia, is characterized by demyelination that affects the central portion of the base of the pons. Central pontine myelinolysis occurs frequently in alcoholism and chronic liver disease. Cl...

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Bibliographic Details
Published inAnnals of the Indian Academy of Neurology Vol. 10; no. 2; pp. 112 - 114
Main Authors Somarajan, A, Paul, M, Kabeer, K, Krishnapriyam, S
Format Journal Article
LanguageEnglish
Published Medknow Publications and Media Pvt. Ltd 01.04.2007
Wolters Kluwer Medknow Publications
Subjects
Alcoholic liver disease
Ataxia
Care and treatment
central pontine myelinolysis
cerebellar ataxia
Complications and side effects
Degeneration
Diagnosis
Diagnosis, Differential
Hyponatremia
Nervous system
India
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Summary:Central pontine myelinolysis (CPM), a neurologic disorder caused most frequently by rapid correction of hyponatremia, is characterized by demyelination that affects the central portion of the base of the pons. Central pontine myelinolysis occurs frequently in alcoholism and chronic liver disease. Clinical features usually reflect damage to the descending motor tracts and include spastic tetraparesis, pseudobulbar paralysis and the locked-in syndrome. Cerebellar ataxia with out weakness and pyramidal signs is extremely unusual. There are only very few reports of central pontine myelinolysis presenting as cerebellar ataxia.
ISSN:0972-2327
1998-3549
DOI:10.4103/0972-2327.33220