Cardiogenic shock in the setting of acute myocardial infarction: Another area of sex disparity?

Cardiogenic shock in the setting of acute myocardial infarction (AMI) carries significant morbidity and mortality, despite advances in pharmacological, mechanical and reperfusion therapies. Studies suggest that there is evidence of sex disparities in the risk profile, management, and outcomes of car...

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Published inWorld journal of cardiology Vol. 13; no. 6; pp. 170 - 176
Main Authors Bukhari, Syed, Fatima, Shumail, Elgendy, Islam Y
Format Journal Article
LanguageEnglish
Published Baishideng Publishing Group Inc 26.06.2021
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Summary:Cardiogenic shock in the setting of acute myocardial infarction (AMI) carries significant morbidity and mortality, despite advances in pharmacological, mechanical and reperfusion therapies. Studies suggest that there is evidence of sex disparities in the risk profile, management, and outcomes of cardiogenic shock complicating AMI. Compared with men, women tend to have more comorbidities, greater variability in symptom presentation and are less likely to receive timely revascularization and mechanical circulatory support. These factors might explain why women tend to have worse outcomes. In this review, we highlight sex-based differences in the prevalence, management, and outcomes of cardiogenic shock due to AMI, and discuss potential ways to mitigate them.
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Author contributions: Bukhari S, Fatima S designed, performed the collection of the data, edited, and wrote the paper; Elgendy IY contributed to the critical revision and editing of the paper.
Corresponding author: Islam Y Elgendy, FACC, FACP, FAHA, MD, Assistant Professor, Consultant Physician-Scientist, Department of Medicine, Weill Cornell Medicine-Qatar, Education City, Qatar Foundation, Doha 24144, Qatar. iyelgendy@gmail.com
ISSN:1949-8462
1949-8462
DOI:10.4330/wjc.v13.i6.170