External quality assessment of serum enzyme activity assays and the effect of calibration on interlaboratory concordance

The design and results of a UK external quality assessment scheme for six enzymes are described, from 21 surveys over a period of 7 years. Improvements in interlaboratory agreement and the adoption of reliable methods are documented. The potential of enzyme calibration materials in further improving...

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Bibliographic Details
Published inAnnals of clinical biochemistry Vol. 23 ( Pt 5); p. 577
Main Authors Bullock, D G, Moss, D W, Whitehead, T P
Format Journal Article
LanguageEnglish
Published England 01.09.1986
Subjects
Enzymes - blood
Humans
Laboratories - standards
Quality Control
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Summary:The design and results of a UK external quality assessment scheme for six enzymes are described, from 21 surveys over a period of 7 years. Improvements in interlaboratory agreement and the adoption of reliable methods are documented. The potential of enzyme calibration materials in further improving numerical concordance between laboratories using different assay conditions, including temperature, is demonstrated and discussed.
ISSN:0004-5632
DOI:10.1177/000456328602300515