Selected serum biochemical parameters and acute phase protein levels in a herd of Saanen goats showing signs of pregnancy toxaemia

The purpose of this study was to examine selected serum biochemical parameters and acute phase protein levels in a herd of Saanen goats showing signs of pregnancy toxaemia. Seventy five female goats were used and divided into three groups. Group 1 (n = 57) (blood serum glucose levels were within the...

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Published inVeterinární medicína Vol. 59; no. 7; pp. 336 - 342
Main Authors Albay, M.K., Karakurum, M.C., Sahinduran, S., Sezer, K., Yildiz, R., Buyukoglu, T.
Format Journal Article
LanguageEnglish
Published Prague Czech Academy of Agricultural Sciences (CAAS) 01.01.2014
Czech Academy of Agricultural Sciences
Subjects
aciduria
Acute phase proteins
Alanine
Alanine transaminase
Amyloid
Aspartate aminotransferase
Blood
Calcium
Calcium (blood)
cytokines
enzymes
Glucose
goat
Goats
Haptoglobin
hydroxybutyrate
Intoxication
ketonuria
minerals
Parameters
Potassium
Pregnancy
Proteins
serum glucose
Sodium
Triglycerides
Tumor necrosis factor-TNF
Tumor necrosis factor-α
Tumors
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Summary:The purpose of this study was to examine selected serum biochemical parameters and acute phase protein levels in a herd of Saanen goats showing signs of pregnancy toxaemia. Seventy five female goats were used and divided into three groups. Group 1 (n = 57) (blood serum glucose levels were within the physiological range), Group 2 (n = 11) (serum glucose values were low) and Group 3 (n = 7) (serum glucose values were high). Goats in Groups 2 and 3 were diagnosed with pregnancy toxaemia. Apart from serum glucose, β-hydroxybutyrate (BHB), triglycerides, blood pH, calcium (Ca), sodium (Na), potassium (K), aspartate aminotransferase (AST), alanine aminotransferase (ALT), haptoglobin (Hp), serum amyloid A (SAA) and tumour necrosis factor-α (TNF-α) were measured in all animals. In Group 3 average Hp and SAA values were found to be significantly (P < 0.001) higher than in Groups 1 and 2, and also higher in Group 2 than in Group 1. Acute phase proteins in goats with pregnancy toxaemia may be used in the course and the prognosis of the disease. The evaluation of acute phase proteins is useful and also quicker in cases of suspected pregnancy intoxication.
ISSN:0375-8427
1805-9392
DOI:10.17221/7620-VETMED