Fallopian tube sperm perfusion: first clinical experience

We have developed an insemination method using a large (4 ml) volume of the inseminate. This method incorporates ovarian stimulation, isolation of an optimal number of motile spermatozoa and, finally, Fallopian tube sperm perfusion (FSP). In a clinical study, 139 couples with various causes of infer...

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Bibliographic Details
Published inHuman reproduction (Oxford) Vol. 7 Suppl 1; p. 19
Main Authors Kahn, J A, von Düring, V, Sunde, A, Sørdal, T, Molne, K
Format Journal Article
LanguageEnglish
Published England 01.06.1992
Subjects
Adult
Fallopian Tubes
Female
Humans
Infertility - etiology
Infertility - therapy
Insemination, Artificial, Homologous - methods
Male
Middle Aged
Perfusion
Spermatozoa
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Summary:We have developed an insemination method using a large (4 ml) volume of the inseminate. This method incorporates ovarian stimulation, isolation of an optimal number of motile spermatozoa and, finally, Fallopian tube sperm perfusion (FSP). In a clinical study, 139 couples with various causes of infertility, had a total of 239 treatment cycles. The pregnancy rate per treatment in groups with endometriosis, ovulation disorders, tubal impairment, combined male and female factors and subnormal sperm quality were low, ranging from 2.7% to 7.7%. In patients with unexplained infertility, the pregnancy rate per treatment was 26.9% and for this group, the pregnancy rate in the first treatment cycle was 37.3%. In the cervical hostility group, two pregnancies occurred after five treatments. FSP seems to be a favourable treatment for couples with cervical hostility or unexplained infertility. About half of the women in these groups conceived after three treatment cycles. FSP is easier to perform and is less expensive than other methods of assisted procreation, such as in vitro fertilization and gamete intra-Fallopian transfer.
ISSN:0268-1161
DOI:10.1093/humrep/7.suppl_1.19