Curcumin inhibits classical swine fever virus replication by interfering with lipid metabolism

• Published in: Veterinary microbiology Vol. 259; p. 109152
• Main Authors: Gao, Ya, Hu, Jia-Huan, Liang, Xiao-Dong, Chen, Jing, Liu, Chun-Chun, Liu, Ya-Yun, Cheng, Yan, Go, Yun Young, Zhou, Bin
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier B.V 01.08.2021; Elsevier BV
• Subjects: Antiviral activity; Classical swine fever virus (CSFV); Curcumin; Dengue fever; Encephalitis; Fever; Hepatitis C; Hog cholera; Innate immunity; Lipid metabolism; Lipids; Metabolism; NF-κB protein; Replication; Signal transduction; Viruses; Innate immunity; Curcumin; Classical swine fever virus (CSFV); Lipid metabolism; Antiviral activity

•Curcumin and curcuminoids inhibits CSFV replication.•Curcumin decreases the lipid accumulation by regulating FASN, lipid droplets and ATF6.•Curcumin promotes innate immunity after viral infection. Although previous reports have shown that Curcumin inhibits many viruses, including some important mem...