Antigens of infectious laryngotracheitis herpesvirus defined by monoclonal antibodies

• Published in: Archives of virology Vol. 115; no. 3/4; pp. 147 - 162
• Main Authors: York, J.J, Sonza, S, Brandon, M.R, Fahey, K.J
• Format: Journal Article
• Language: English
• Published: Austria 01.01.1990
• Subjects: Animals; Antibodies, Monoclonal - biosynthesis; Antibodies, Monoclonal - immunology; Antigens, Viral - immunology; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; epitopes; Fluorescent Antibody Technique; glycoproteins; Glycoproteins - immunology; Herpesvirus 1, Gallid - drug effects; Herpesvirus 1, Gallid - immunology; Iltovirus; Immunoblotting; Mice; Mice, Inbred BALB C; monoclonal antibodies; Neutralization Tests; surface antigens; Tunicamycin - pharmacology; viral antigens

Monoclonal antibodies to glycoprotein and protein antigens of infectious laryngotracheitis virus (ILTV) were divided into five groups on the basis of their reactivity in immunofluorescence and Western blotting. Group I antibodies recognised a single band of 60 k and Group II antibodies recognised ba...