Enzymatic synthesis of biologically active compounds: synthesis of castanospermine derivatives

A three‐step enzyme‐catalyzed synthesis of 7‐O‐butyrylcastanospermine from castanospermine has been developed.

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Bibliographic Details
Published inBiotechnology progress Vol. 6; no. 3; pp. 203 - 204
Main Authors Margolin, A.L. (Merrell Dow Research Institute, Indianapolis, Indiana), Delinck, D.L
Format Journal Article
LanguageEnglish
Published USA American Chemical Society 01.05.1990
Subjects
7-O-BUTYRYLCASTANOSPERMINE
acquired immune deficiency syndrome
ACTIVIDAD ENZIMATICA
ACTIVITE ENZYMATIQUE
AGENTES ANTINEOPLASTICOS
ALCALOIDE
ALCALOIDES
ALKALOIDS
ANTINEOPLASTIC AGENTS
antineoplastic drugs
ANTIVIRAL
ANTIVIRAL AGENTS
castanospermine
DRUG PLANTS
ENZYMIC ACTIVITY
ESTERASAS
ESTERASE
ESTERASES
human immunodeficiency virus
MEDICAMENT CYTOSTATIQUE
MEDICINAL PLANTS
PLANTAS MEDICINALES
PLANTE MEDICINALE
SERINE PROTEINASES
SUBTILISIN
TRIACILGLICEROL LIPASA
TRIACYLGLYCEROL LIPASE
VIRICIDAS
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Summary:A three‐step enzyme‐catalyzed synthesis of 7‐O‐butyrylcastanospermine from castanospermine has been developed.
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ArticleID:BTPR5420060308
ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ISSN:8756-7938
1520-6033
DOI:10.1021/bp00003a007