Comparative study between kidney transplantation with deceased donor expanded criteria and donor standard criteria in a single center in Brazil

• Published in: Brazilian Journal of Nephrology Vol. 38; no. 3; pp. 334 - 343
• Main Authors: Mota, Luana Soriano, Oliveira, Claudia Maria Costa de, Pinheiro, Junior, Francisco Martho Leal, Santos, Larissa Costa de Oliveira, Nóbrega, Danilo Gonçalves, Fernandes, Paula Fbc, Costa, Alda Angélica de Melo, Silva, Sônia Leite da
• Format: Journal Article
• Language: English
• Published: Brazil Sociedade Brasileira de Nefrologia 01.07.2016
• Subjects: Brazil; Cohort Studies; delayed graft function; Delayed Graft Function - epidemiology; Delayed Graft Function - physiopathology; Donor Selection - methods; Donor Selection - standards; Female; graft rate; Humans; Kidney Function Tests; Kidney Transplantation; Male; Middle Aged; Prevalence; Retrospective Studies; Survival Rate; Time Factors
• ISSN: 0101-2800; 2175-8239; 2175-8239
• DOI: 10.5935/0101-2800.20160051

Kidney transplants with expanded criteria donor have been associated with improved patient survival compared to those who remain on dialysis. To compare renal function and survival of the kidney graft of deceased donor with expanded criteria and standard criteria over a year in a single transplant center. 255 kidney transplant recipients with deceased donor were included in the study between the years 2011 to 2013 and they were separated into two groups according to the type of donor (expanded criteria donor - ECD - and standard criteria donor - SCD). 231 deceased donor transplants (90.6%) were performed with standard criteria donor (SCD) and 24 (9.4%) with expanded criteria donor (ECD). There was no difference in the prevalence of delayed graft function - DGF - (62.9% vs. 70.8%; p = 0.44). Expanded criteria donor group had lower glomerular filtration rate (GFR) at the end of the 1st year (56.8 ± 26.9 vs. 76.9 ± 23.7; p = 0.001). Patient survival was significantly lower in the ECD group, but the graft survival was not different after death-censored analysis. The ECD group was associated with significantly lower levels of GFR during the first year of transplant and a lower patient survival at the 1st year when compared to the SCD.