A review of pulmonary autograft external support in the Ross procedure

• Published in: Expert review of medical devices Vol. 16; no. 11; p. 981
• Main Authors: Chauvette, Vincent, Chamberland, Marie-Ève, El-Hamamsy, Ismail
• Format: Journal Article
• Language: English
• Published: England 02.11.2019
• Subjects: Aortic Valve - surgery; Autografts - surgery; Dilatation, Pathologic; Humans; Lung - surgery; Tissue Scaffolds; Transcatheter Aortic Valve Replacement - methods; pulmonary autograft; cardiac surgery; Ross procedure; devices; dilatation
• ISSN: 1745-2422
• DOI: 10.1080/17434440.2019.1685380

: Although the Ross procedure offers several advantages over standard prosthetic AVR, its use remains limited. The risk of pulmonary autograft dilatation requiring reintervention remains one of the main concerns. Consequently, multiple techniques have been developed in attempt to mitigate this complication. : This article reviews the incidence of pulmonary autograft dilatation, its risk factors and pathophysiology. The techniques of external pulmonary autograft support are discussed along with their respective advantages and limitations. Finally, future areas of research and developments are examined. : The risk of autograft dilatation is mainly prevalent in patients with aortic regurgitation and a dilated aortic annulus. In these selected patients, an external support may prevent dilatation of the autograft. However, any permanent support potentially restricts autograft root motion, mitigating some of the advantages associated with the Ross procedure. A bioresorbable matrix that could support the root during its initial adaptative phase could alleviate this problem. In our opinion, aggressive blood pressure control during the first postoperative year along with annular and sino-tubular junction support in selected patients provides optimal stability of autograft root dimensions while preserving root dynamics. Serial imaging and clinical follow-up are necessary to define the role of these various strategies.