Obesity: Lifestyle management, bariatric surgery, drugs, and the therapeutic exploitation of gut hormones
Obesity is on the rise and the pursuit of efficient and safe treatment is ongoing. Available anti-obesity medical therapies have so far proved to be disappointing, whereas bariatric surgery is leading the way and offers long-term health benefits. Part of the success of bariatric surgery is thought t...
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Published in | Postgraduate medicine Vol. 127; no. 5; p. 494 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
England
03.09.2015
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Subjects | |
Online Access | Get more information |
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Summary: | Obesity is on the rise and the pursuit of efficient and safe treatment is ongoing. Available anti-obesity medical therapies have so far proved to be disappointing, whereas bariatric surgery is leading the way and offers long-term health benefits. Part of the success of bariatric surgery is thought to be mediated by gut hormones. A better understanding of the role of gut hormones within the gut-brain signaling pathway in the control of hunger, satiety, and energy homeostasis, has led to their therapeutic exploitation as possible anti-obesity drugs. In this review, we provide a summary of currently available treatment options for obesity from simple lifestyle modifications and bariatric surgery to traditional and novel medical therapies. |
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ISSN: | 1941-9260 |
DOI: | 10.1080/00325481.2015.1048181 |