Mandibular advancement device: Effectiveness and dental side effects. A real-life study

• Published in: Cranio Vol. 40; no. 2; p. 97
• Main Authors: Chen, Aoben, Burger, Maud S, Rietdijk-Smulders, Margriet A W J, Smeenk, Frank W J M
• Format: Journal Article
• Language: English
• Published: England 04.03.2022
• Subjects: Continuous Positive Airway Pressure; Humans; Mandibular Advancement - adverse effects; Occlusal Splints; Retrospective Studies; Treatment Outcome; dental; mandibular advancement device; snoring; polysomnography; oral appliances; Obstructive sleep apnea; continuous positive airway pressure; retrospective study
• ISSN: 2151-0903
• DOI: 10.1080/08869634.2019.1708610

: To investigate the effectiveness and adverse events of mandibular advancement device (MAD) in patients with obstructive sleep apnea (OSA) and to identify predictive clinical parameters for therapy success. : A retrospective analysis of 318 patients indicated for MAD therapy, observed in a large teaching hospital in the Netherlands. : Ninety-seven patients (65.5%) achieved therapy success. A significant decrease in AHI (apnea-hypopnea index) and OSA-related symptoms was observed. None of the analyzed OSA-characteristics proved to be a significant predictive parameter for therapy success. Side-effects were reported in 54.4% of the patients, with temporomandibular dysfunction (27.0%) being the most frequent. Seventy-four patients (23.3%) discontinued treatment due to side-effects or therapy failure. : MAD proved to be effective in the treatment of OSA and can be a viable alternative to CPAP in patients with severe OSA. Side-effects were relatively common and led to termination of therapy in 1 out of 10 cases.