Assessment of Red Cell Distribution Width, Platelet/lymphocyte Ratio, Systemic Immune-inflammation Index, and Neutrophil/lymphocyte Ratio Values in Patients with Central Retinal Artery Occlusion
To evaluate complete blood count (CBC)-derived inflammatory indices in central retinal artery occlusion (CRAO). A total of 42 patients with CRAO (CRAO group) and 42 age- and sex-matched subjects without CRAO (Control group) were included. CBC parameters including red cell distribution width (RDW) le...
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Published in | Ocular immunology and inflammation Vol. 30; no. 7-8; pp. 1940 - 1944 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
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England
Taylor & Francis
17.11.2022
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ISSN | 0927-3948 1744-5078 1744-5078 |
DOI | 10.1080/09273948.2021.1976219 |
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Abstract | To evaluate complete blood count (CBC)-derived inflammatory indices in central retinal artery occlusion (CRAO).
A total of 42 patients with CRAO (CRAO group) and 42 age- and sex-matched subjects without CRAO (Control group) were included. CBC parameters including red cell distribution width (RDW) levels were assayed. Platelet/lymphocyte ratio (PLR), systemic immune-inflammation index (SII) and neutrophil/ lymphocyte ratio (NLR) were calculated.
RDW, PLR, SII and NLR values were significantly higher in CRAO group than control group [15.2 ± 1.47% vs 13.96 ± 1.13% (p < .001), 127.94 ± 48.21 vs 101.16 ± 24.84 (p = .008), 667.11 ± 357.84 vs 493.44 ± 207.07 (p = .008), 2.70 ± 1.27 vs 2.13 ± 0.83 (p = .018), respectively]. In multivariate analysis only RDW was independent predictor for CRAO (OR 2.317, p < .001). On ROC analysis, area under curve of RDW, PLR, SII, and NLR for CRAO were 0.761, 0.685, 0.622 and 0.618, respectively.
RDW seems superior to other inflammatory indices to predict CRAO. |
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AbstractList | To evaluate complete blood count (CBC)-derived inflammatory indices in central retinal artery occlusion (CRAO).
A total of 42 patients with CRAO (CRAO group) and 42 age- and sex-matched subjects without CRAO (Control group) were included. CBC parameters including red cell distribution width (RDW) levels were assayed. Platelet/lymphocyte ratio (PLR), systemic immune-inflammation index (SII) and neutrophil/ lymphocyte ratio (NLR) were calculated.
RDW, PLR, SII and NLR values were significantly higher in CRAO group than control group [15.2 ± 1.47% vs 13.96 ± 1.13% (p < .001), 127.94 ± 48.21 vs 101.16 ± 24.84 (p = .008), 667.11 ± 357.84 vs 493.44 ± 207.07 (p = .008), 2.70 ± 1.27 vs 2.13 ± 0.83 (p = .018), respectively]. In multivariate analysis only RDW was independent predictor for CRAO (OR 2.317, p < .001). On ROC analysis, area under curve of RDW, PLR, SII, and NLR for CRAO were 0.761, 0.685, 0.622 and 0.618, respectively.
RDW seems superior to other inflammatory indices to predict CRAO. To evaluate complete blood count (CBC)-derived inflammatory indices in central retinal artery occlusion (CRAO).PURPOSETo evaluate complete blood count (CBC)-derived inflammatory indices in central retinal artery occlusion (CRAO).A total of 42 patients with CRAO (CRAO group) and 42 age- and sex-matched subjects without CRAO (Control group) were included. CBC parameters including red cell distribution width (RDW) levels were assayed. Platelet/lymphocyte ratio (PLR), systemic immune-inflammation index (SII) and neutrophil/ lymphocyte ratio (NLR) were calculated.METHODSA total of 42 patients with CRAO (CRAO group) and 42 age- and sex-matched subjects without CRAO (Control group) were included. CBC parameters including red cell distribution width (RDW) levels were assayed. Platelet/lymphocyte ratio (PLR), systemic immune-inflammation index (SII) and neutrophil/ lymphocyte ratio (NLR) were calculated.RDW, PLR, SII and NLR values were significantly higher in CRAO group than control group [15.2 ± 1.47% vs 13.96 ± 1.13% (p < .001), 127.94 ± 48.21 vs 101.16 ± 24.84 (p = .008), 667.11 ± 357.84 vs 493.44 ± 207.07 (p = .008), 2.70 ± 1.27 vs 2.13 ± 0.83 (p = .018), respectively]. In multivariate analysis only RDW was independent predictor for CRAO (OR 2.317, p < .001). On ROC analysis, area under curve of RDW, PLR, SII, and NLR for CRAO were 0.761, 0.685, 0.622 and 0.618, respectively.RESULTSRDW, PLR, SII and NLR values were significantly higher in CRAO group than control group [15.2 ± 1.47% vs 13.96 ± 1.13% (p < .001), 127.94 ± 48.21 vs 101.16 ± 24.84 (p = .008), 667.11 ± 357.84 vs 493.44 ± 207.07 (p = .008), 2.70 ± 1.27 vs 2.13 ± 0.83 (p = .018), respectively]. In multivariate analysis only RDW was independent predictor for CRAO (OR 2.317, p < .001). On ROC analysis, area under curve of RDW, PLR, SII, and NLR for CRAO were 0.761, 0.685, 0.622 and 0.618, respectively.RDW seems superior to other inflammatory indices to predict CRAO.CONCLUSIONRDW seems superior to other inflammatory indices to predict CRAO. |
Author | Elbeyli, Ahmet Dogan, Emine Ozcan, Deniz Ozarslan Kurtul, Bengi Ece Ozcan, Sait Coskun |
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Keywords | systemic immune-inflammation index blood cell count platelet/lymphocyte ratio Central retinal artery occlusion Inflammation neutrophil/lymphocyte ratio red cell distribution width |
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Snippet | To evaluate complete blood count (CBC)-derived inflammatory indices in central retinal artery occlusion (CRAO).
A total of 42 patients with CRAO (CRAO group)... To evaluate complete blood count (CBC)-derived inflammatory indices in central retinal artery occlusion (CRAO).PURPOSETo evaluate complete blood count... |
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SubjectTerms | blood cell count Blood Platelets Central retinal artery occlusion Erythrocyte Indices Humans Inflammation Lymphocytes neutrophil/lymphocyte ratio Neutrophils platelet/lymphocyte ratio red cell distribution width Retinal Vein Occlusion - diagnosis systemic immune-inflammation index |
Title | Assessment of Red Cell Distribution Width, Platelet/lymphocyte Ratio, Systemic Immune-inflammation Index, and Neutrophil/lymphocyte Ratio Values in Patients with Central Retinal Artery Occlusion |
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