Assessment of Red Cell Distribution Width, Platelet/lymphocyte Ratio, Systemic Immune-inflammation Index, and Neutrophil/lymphocyte Ratio Values in Patients with Central Retinal Artery Occlusion

To evaluate complete blood count (CBC)-derived inflammatory indices in central retinal artery occlusion (CRAO). A total of 42 patients with CRAO (CRAO group) and 42 age- and sex-matched subjects without CRAO (Control group) were included. CBC parameters including red cell distribution width (RDW) le...

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Published inOcular immunology and inflammation Vol. 30; no. 7-8; pp. 1940 - 1944
Main Authors Elbeyli, Ahmet, Kurtul, Bengi Ece, Ozcan, Deniz Ozarslan, Ozcan, Sait Coskun, Dogan, Emine
Format Journal Article
LanguageEnglish
Published England Taylor & Francis 17.11.2022
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ISSN0927-3948
1744-5078
1744-5078
DOI10.1080/09273948.2021.1976219

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Abstract To evaluate complete blood count (CBC)-derived inflammatory indices in central retinal artery occlusion (CRAO). A total of 42 patients with CRAO (CRAO group) and 42 age- and sex-matched subjects without CRAO (Control group) were included. CBC parameters including red cell distribution width (RDW) levels were assayed. Platelet/lymphocyte ratio (PLR), systemic immune-inflammation index (SII) and neutrophil/ lymphocyte ratio (NLR) were calculated. RDW, PLR, SII and NLR values were significantly higher in CRAO group than control group [15.2 ± 1.47% vs 13.96 ± 1.13% (p < .001), 127.94 ± 48.21 vs 101.16 ± 24.84 (p = .008), 667.11 ± 357.84 vs 493.44 ± 207.07 (p = .008), 2.70 ± 1.27 vs 2.13 ± 0.83 (p = .018), respectively]. In multivariate analysis only RDW was independent predictor for CRAO (OR 2.317, p < .001). On ROC analysis, area under curve of RDW, PLR, SII, and NLR for CRAO were 0.761, 0.685, 0.622 and 0.618, respectively. RDW seems superior to other inflammatory indices to predict CRAO.
AbstractList To evaluate complete blood count (CBC)-derived inflammatory indices in central retinal artery occlusion (CRAO). A total of 42 patients with CRAO (CRAO group) and 42 age- and sex-matched subjects without CRAO (Control group) were included. CBC parameters including red cell distribution width (RDW) levels were assayed. Platelet/lymphocyte ratio (PLR), systemic immune-inflammation index (SII) and neutrophil/ lymphocyte ratio (NLR) were calculated. RDW, PLR, SII and NLR values were significantly higher in CRAO group than control group [15.2 ± 1.47% vs 13.96 ± 1.13% (p < .001), 127.94 ± 48.21 vs 101.16 ± 24.84 (p = .008), 667.11 ± 357.84 vs 493.44 ± 207.07 (p = .008), 2.70 ± 1.27 vs 2.13 ± 0.83 (p = .018), respectively]. In multivariate analysis only RDW was independent predictor for CRAO (OR 2.317, p < .001). On ROC analysis, area under curve of RDW, PLR, SII, and NLR for CRAO were 0.761, 0.685, 0.622 and 0.618, respectively. RDW seems superior to other inflammatory indices to predict CRAO.
To evaluate complete blood count (CBC)-derived inflammatory indices in central retinal artery occlusion (CRAO).PURPOSETo evaluate complete blood count (CBC)-derived inflammatory indices in central retinal artery occlusion (CRAO).A total of 42 patients with CRAO (CRAO group) and 42 age- and sex-matched subjects without CRAO (Control group) were included. CBC parameters including red cell distribution width (RDW) levels were assayed. Platelet/lymphocyte ratio (PLR), systemic immune-inflammation index (SII) and neutrophil/ lymphocyte ratio (NLR) were calculated.METHODSA total of 42 patients with CRAO (CRAO group) and 42 age- and sex-matched subjects without CRAO (Control group) were included. CBC parameters including red cell distribution width (RDW) levels were assayed. Platelet/lymphocyte ratio (PLR), systemic immune-inflammation index (SII) and neutrophil/ lymphocyte ratio (NLR) were calculated.RDW, PLR, SII and NLR values were significantly higher in CRAO group than control group [15.2 ± 1.47% vs 13.96 ± 1.13% (p < .001), 127.94 ± 48.21 vs 101.16 ± 24.84 (p = .008), 667.11 ± 357.84 vs 493.44 ± 207.07 (p = .008), 2.70 ± 1.27 vs 2.13 ± 0.83 (p = .018), respectively]. In multivariate analysis only RDW was independent predictor for CRAO (OR 2.317, p < .001). On ROC analysis, area under curve of RDW, PLR, SII, and NLR for CRAO were 0.761, 0.685, 0.622 and 0.618, respectively.RESULTSRDW, PLR, SII and NLR values were significantly higher in CRAO group than control group [15.2 ± 1.47% vs 13.96 ± 1.13% (p < .001), 127.94 ± 48.21 vs 101.16 ± 24.84 (p = .008), 667.11 ± 357.84 vs 493.44 ± 207.07 (p = .008), 2.70 ± 1.27 vs 2.13 ± 0.83 (p = .018), respectively]. In multivariate analysis only RDW was independent predictor for CRAO (OR 2.317, p < .001). On ROC analysis, area under curve of RDW, PLR, SII, and NLR for CRAO were 0.761, 0.685, 0.622 and 0.618, respectively.RDW seems superior to other inflammatory indices to predict CRAO.CONCLUSIONRDW seems superior to other inflammatory indices to predict CRAO.
Author Elbeyli, Ahmet
Dogan, Emine
Ozcan, Deniz Ozarslan
Kurtul, Bengi Ece
Ozcan, Sait Coskun
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Keywords systemic immune-inflammation index
blood cell count
platelet/lymphocyte ratio
Central retinal artery occlusion
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neutrophil/lymphocyte ratio
red cell distribution width
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Snippet To evaluate complete blood count (CBC)-derived inflammatory indices in central retinal artery occlusion (CRAO). A total of 42 patients with CRAO (CRAO group)...
To evaluate complete blood count (CBC)-derived inflammatory indices in central retinal artery occlusion (CRAO).PURPOSETo evaluate complete blood count...
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SubjectTerms blood cell count
Blood Platelets
Central retinal artery occlusion
Erythrocyte Indices
Humans
Inflammation
Lymphocytes
neutrophil/lymphocyte ratio
Neutrophils
platelet/lymphocyte ratio
red cell distribution width
Retinal Vein Occlusion - diagnosis
systemic immune-inflammation index
Title Assessment of Red Cell Distribution Width, Platelet/lymphocyte Ratio, Systemic Immune-inflammation Index, and Neutrophil/lymphocyte Ratio Values in Patients with Central Retinal Artery Occlusion
URI https://www.tandfonline.com/doi/abs/10.1080/09273948.2021.1976219
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