Assessment of Red Cell Distribution Width, Platelet/lymphocyte Ratio, Systemic Immune-inflammation Index, and Neutrophil/lymphocyte Ratio Values in Patients with Central Retinal Artery Occlusion

• Published in: Ocular immunology and inflammation Vol. 30; no. 7-8; pp. 1940 - 1944
• Main Authors: Elbeyli, Ahmet, Kurtul, Bengi Ece, Ozcan, Deniz Ozarslan, Ozcan, Sait Coskun, Dogan, Emine
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis 17.11.2022
• Subjects: blood cell count; Blood Platelets; Central retinal artery occlusion; Erythrocyte Indices; Humans; Inflammation; Lymphocytes; neutrophil/lymphocyte ratio; Neutrophils; platelet/lymphocyte ratio; red cell distribution width; Retinal Vein Occlusion - diagnosis; systemic immune-inflammation index; systemic immune-inflammation index; blood cell count; platelet/lymphocyte ratio; Central retinal artery occlusion; Inflammation; neutrophil/lymphocyte ratio; red cell distribution width
• ISSN: 0927-3948; 1744-5078; 1744-5078
• DOI: 10.1080/09273948.2021.1976219

To evaluate complete blood count (CBC)-derived inflammatory indices in central retinal artery occlusion (CRAO). A total of 42 patients with CRAO (CRAO group) and 42 age- and sex-matched subjects without CRAO (Control group) were included. CBC parameters including red cell distribution width (RDW) levels were assayed. Platelet/lymphocyte ratio (PLR), systemic immune-inflammation index (SII) and neutrophil/ lymphocyte ratio (NLR) were calculated. RDW, PLR, SII and NLR values were significantly higher in CRAO group than control group [15.2 ± 1.47% vs 13.96 ± 1.13% (p < .001), 127.94 ± 48.21 vs 101.16 ± 24.84 (p = .008), 667.11 ± 357.84 vs 493.44 ± 207.07 (p = .008), 2.70 ± 1.27 vs 2.13 ± 0.83 (p = .018), respectively]. In multivariate analysis only RDW was independent predictor for CRAO (OR 2.317, p < .001). On ROC analysis, area under curve of RDW, PLR, SII, and NLR for CRAO were 0.761, 0.685, 0.622 and 0.618, respectively. RDW seems superior to other inflammatory indices to predict CRAO.