The relationship of Akathisia with treatment emergent suicidality among patients with first-episode schizophrenia treated with haloperidol or risperidone

Akathisia as well as younger age, early illness onset and discharge are important risk factors for suicidality in patients with first-episode schizophrenia. The aim of the present study was to analyze on a single case basis the relationship between a sudden increase in suicidality, anxiety symptoms,...

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Published inPharmacopsychiatry Vol. 45; no. 7; p. 292
Main Authors Seemüller, F, Lewitzka, U, Bauer, M, Meyer, S, Musil, R, Schennach, R, Riedel, M, Doucette, S, Möller, H-J
Format Journal Article
LanguageEnglish
Published Germany 01.11.2012
Subjects
Adolescent
Adult
Age Factors
Akathisia, Drug-Induced - psychology
Antipsychotic Agents - adverse effects
Antipsychotic Agents - therapeutic use
Anxiety - chemically induced
Female
Haloperidol - adverse effects
Haloperidol - therapeutic use
Humans
Male
Middle Aged
Psychiatric Status Rating Scales - statistics & numerical data
Risk Factors
Risperidone - adverse effects
Risperidone - therapeutic use
Schizophrenia - drug therapy
Schizophrenic Psychology
Suicidal Ideation
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Summary:Akathisia as well as younger age, early illness onset and discharge are important risk factors for suicidality in patients with first-episode schizophrenia. The aim of the present study was to analyze on a single case basis the relationship between a sudden increase in suicidality, anxiety symptoms, medication dosing and clinician- and patient-rated akathisia. A small subsample of patients demonstrated a positive relationship between suicidality and akathisia scores within the titration period of the study medication.
ISSN:1439-0795
DOI:10.1055/s-0032-1309004