CSF -contacting and other somatostatin-immunoreactive neurons in the brains of Anguilla anguilla, Phoxinus phoxinus, and Salmo gairdneri (Teleostei)

• Published in: Cell and tissue research Vol. 233; no. 2; pp. 319 - 334
• Main Authors: Vigh-Teichmann, I, Vigh, B, Korf, H.W, Oksche, A
• Format: Journal Article
• Language: English
• Published: Germany 01.01.1983
• Subjects: Actinopterygii; Animals; Brain Chemistry; cerebrospinal fluid; Cyprinidae - physiology; Diencephalon - analysis; Eels - physiology; Fishes - physiology; Immunoenzyme Techniques; Mesencephalon - analysis; Neurons - analysis; Somatostatin - analysis; Somatostatin - cerebrospinal fluid; Species Specificity; Trout - physiology
• ISSN: 0302-766X; 1432-0878
• DOI: 10.1007/BF00238299

A system of somatostatin-immunoreactive neurons was demonstrated in the brains of the eel, Anguilla anguilla, the European minnow, Phoxinus phoxinus, and the rainbow trout, Salmo gairdneri, by means of the light-microscopic indirect immunoperoxidase technique. In the anterior periventricular nucleus, somatostatin-immunoreactive cerebrospinal fluid (CSF)-contacting neurons display intensely stained intraventricular dendritic protrusions, perikarya, and axonal processes. The latter taper into a somatostatin-immunoreactive fiber plexus extending to the infundibulum, the proximal neurohypophysis, and the lateral and mammillary recesses. In addition, somatostatin-immunoreactive neurons were demonstrated in the magnocellular preoptic, entopeduncular and dorsolateral thalamic nuclei, further in the pretectal area and the ventrolateral tegmentum. Somatostatin-immunoreactive fiber bundles project via the stria medullaris toward the habenular nucleus; they also course in the dorsomedial-ventrolateral direction at the level of the pretectal-tegmental area, and within the ventral and dorsal tegmentum. The presence of somatostatin in a variety of different neurons of the teleost brain is discussed in connection with their tentative inhibitory function. The CSF-contacting neurons of the anterior periventricular nucleus are supposed to function as sensors that pass information from the CSF to the somatostatin system of the hypothalamus and/or other components of the neuroendocrine apparatus.