"Anemia and Response to Neoadjuvant Chemotherapy in Breast Cancer Patients"
We analyzed the effect of anemia on tumor response of patients with primary invasive breast cancer (BC) receiving neoadjuvant chemotherapy (NACT). The patient collective was very homogenous; finally, 74 BC patients with identical medication and duration of NACT were enrolled. After completion of NAC...
Saved in:
Published in | Cancer investigation Vol. 39; no. 6-7; pp. 457 - 465 |
---|---|
Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
England
Taylor & Francis
09.08.2021
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | We analyzed the effect of anemia on tumor response of patients with primary invasive breast cancer (BC) receiving neoadjuvant chemotherapy (NACT). The patient collective was very homogenous; finally, 74 BC patients with identical medication and duration of NACT were enrolled. After completion of NACT, 49 patients (66.2%) had a post-NACT Hb level <12 g/dl. In the anemic group, we found a tendency of lower median tumor response compared to nonanemic patients at this time (15 versus 17 mm, retrospectively, p = 0.18). Age at diagnosis significantly correlated with the difference of Hb [before initiation - after completion of NACT] (correlation coefficient = 0.40, p < 0.001). |
---|---|
Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0735-7907 1532-4192 |
DOI: | 10.1080/07357907.2021.1928166 |