SYNTHESIS OF 7-FORMYLINDOLE USING THE BARTOLI INDOLE METHODOLOGY

The Bartoli methodology provides a convenient route for the synthesis of 7-formylindole, either indirectly via an improved metalation of 7-bromoindole using sodium hydride/butyllithium or two equivalents of butyllithium or directly by use of an acetal protected 2-nitrobenzaldehyde and vinylmagnesium...

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Bibliographic Details
Published inSynlett no. 1; pp. 79 - 80
Main Authors DOBSON, DR, GILMORE, J, LONG, DA
Format Journal Article
LanguageEnglish
Published STUTTGART Thieme Medical Publishers 01.01.1992
Subjects
Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
CHEMISTRY
7-SUBSTITUTED INDOLES
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Summary:The Bartoli methodology provides a convenient route for the synthesis of 7-formylindole, either indirectly via an improved metalation of 7-bromoindole using sodium hydride/butyllithium or two equivalents of butyllithium or directly by use of an acetal protected 2-nitrobenzaldehyde and vinylmagnesium bromide.
ISSN:0936-5214
DOI:10.1055/s-1992-21273