Pancreatic cancer with ovarian metastases: A case report and review of the literature

Pancreatic cancer with ovarian metastases is rare and easily misdiagnosed. Most patients are first diagnosed with ovarian cancer. We report a rare case of ovarian metastases secondary to pancreatic adenocarcinoma. We also review the literature to analyze the clinical characteristics of, diagnostic m...

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Bibliographic Details
Published inWorld journal of clinical cases Vol. 8; no. 21; pp. 5380 - 5388
Main Authors Wang, Shun-Da, Zhu, Liang, Wu, Huan-Wen, Dai, Meng-Hua, Zhao, Yu-Pei
Format Journal Article
LanguageEnglish
Published United States Baishideng Publishing Group Inc 06.11.2020
Subjects
Case Report
Ovary
Case report
Metastasis
Pancreas
Pancreatic cancer
Ovarian cancer
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Summary:Pancreatic cancer with ovarian metastases is rare and easily misdiagnosed. Most patients are first diagnosed with ovarian cancer. We report a rare case of ovarian metastases secondary to pancreatic adenocarcinoma. We also review the literature to analyze the clinical characteristics of, diagnostic methods for, and perioperative management strategies for this rare malignancy. A 48-year-old woman with an abdominal mass presented to our hospital. Computed tomography revealed lesions in the pancreas and lower abdomen. Radiological examination and histological investigation of biopsy specimens revealed either an ovarian metastasis from a pancreatic neoplasm or two primary tumors, with metastasis strongly suspected. The patient simultaneously underwent distal pancreatectomy plus splenectomy by a general surgeon and salpingo-oophorectomy with hysterectomy by a gynecologist. Histological examination of the surgical specimen revealed a pancreatic adenocarcinoma (intermediate differentiation, mucinous) and a metastatic mucinous adenocarci-noma in the ovary. For this rare tumor, surgical resection is the most effective treatment, and the final diagnosis depends on tumor pathology.
Bibliography:Corresponding author: Meng-Hua Dai, MD, Doctor, Professor, Surgeon, Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, No. 1 Shuai Fu Yuan, Dongcheng District, Beijing 100730, China. daimh@pumch.cn
Supported by CAMS Innovation Fund for Medical Sciences, No. 2016-I2M-3-005; and Beijing Municipal Science & Technology Commission, No. Z171100001017017018.
Author contributions: Dai MH and Zhao YP designed the research and approved the final manuscript; Dai MH developed the literature search and carried out the statistical analysis; Wang SD carried out data extraction; Wu HW analyzed the pathology pictures; Zhu L helped to prepare the radiology images; Wang SD wrote the manuscript; all authors read and approved the final manuscript.
ISSN:2307-8960
2307-8960
DOI:10.12998/wjcc.v8.i21.5380