Engineering thermoresponsive polyether-based nanogels for temperature dependent skin penetration

Highly biocompatible thermoresponsive nanogels (tNGs) based on oligo ethylene glycol (OEG) as thermoresponsive unit and dendritic polyglycerol (dPG) as cross-linker, were precisely engineered in terms of size and volume phase transition temperature (VPTT). Preliminary uptake studies into human skin...

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Bibliographic Details
Published inPolymer chemistry Vol. 6; no. 32; pp. 5827 - 5831
Main Authors Asadian-Birjand, M., Bergueiro, J., Rancan, F., Cuggino, J. C., Mutihac, R.-C., Achazi, K., Dernedde, J., Blume-Peytayi, U., Vogt, A., Calderón, M.
Format Journal Article
LanguageEnglish
Published 01.01.2015
Subjects
Biocompatibility
Ethylene glycol
Human behavior
Nanostructure
Penetration
Polyglycerols
Polymer chemistry
Uptakes
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Summary:Highly biocompatible thermoresponsive nanogels (tNGs) based on oligo ethylene glycol (OEG) as thermoresponsive unit and dendritic polyglycerol (dPG) as cross-linker, were precisely engineered in terms of size and volume phase transition temperature (VPTT). Preliminary uptake studies into human skin were realized to show the temperature-dependent internalization behavior of these systems.
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ISSN:1759-9954
1759-9962
DOI:10.1039/C5PY00924C