Encapsulating peritoneal sclerosis in paediatric peritoneal dialysis patients

• Published in: Nephrology (Carlton, Vic.) Vol. 10; no. 4; pp. 341 - 343
• Main Authors: EKIM, MESIHA, FITÖZ, SUAT, YAGMURLU, AYDIN, ENSARI, ARZU, YÜKSEL, SELÇUK, ACAR, BANU, ÖZÇAKAR, Z BIRSIN, KENDIRLI, TANIL, BINGÖLER, BAHAR, YALÇINKAYA, FATOŞ
• Format: Journal Article
• Language: English
• Published: Melbourne, Australia Blackwell Science Pty 01.08.2005
• Subjects: Adolescent; chronic peritoneal dialysis; continuous ambulatory peritoneal dialysis; encapsulating peritoneal sclerosis; Humans; Male; Parenteral Nutrition, Total; Peritoneal Dialysis - adverse effects; Peritoneal Dialysis, Continuous Ambulatory - adverse effects; Peritoneal Diseases - etiology; Peritoneal Diseases - therapy; Peritoneum - pathology; Peritonitis - etiology; sclerosing encapsulating peritonitis; Sclerosis
• ISSN: 1320-5358; 1440-1797
• DOI: 10.1111/j.1440-1797.2005.00416.x

Encapsulating peritoneal sclerosis (EPS) is a serious complication of chronic peritoneal dialysis (CPD). In contrast to the adult population, there are few studies regarding EPS in paediatric CPD patients, and the majority of reported patients are from Japan. The aim of the present report is to define the incidence of EPS in our paediatric CPD patients and to describe the clinical and laboratory characteristics. A total of 104 paediatric patients were followed from November 1989 to November 2003 and two were diagnosed as EPS (1.9%). The dialysis periods of these patients were 45 and 53 months with 6 and 8 peritonitis episodes, respectively. Clinical signs of EPS developed 7 and 14 days after the removal of the dialysis catheter, and CPD was replaced by haemodialysis because of persistent peritonitis. One patient was well after surgical management but died 6 months later. The second patient who was treated with prednisolone remained well at 16 months. In conclusion, EPS is a rare but important complication of CPD. We recommend that all patients on CPD who develop ultrafiltration failure be evaluated radiologically for the occurence of EPS. Management should be tailored to the individual patient.