Stem cell therapy for diabetes

Stem cell therapy holds immense promise for the treatment of patients with diabetes mellitus. Research on the ability of human embryonic stem cells to differentiate into islet cells has defined the developmental stages and transcription factors involved in this process. However, the clinical applica...

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Bibliographic Details
Published inIndian journal of endocrinology and metabolism Vol. 16; no. Suppl 2; pp. S227 - S229
Main Authors Lee, K O, Gan, S U, Calne, R Y
Format Journal Article
LanguageEnglish
Published India Medknow Publications and Media Pvt. Ltd 01.12.2012
Medknow Publications & Media Pvt Ltd
Wolters Kluwer Medknow Publications
Subjects
Care and treatment
Diabetes
Embryonic stem cell
Gene therapy
Health aspects
induced pluripotent stem cell
mesenchymal stem cell
Mini Review
Stem cells
India
Embryonic stem cell
mesenchymal stem cell
induced pluripotent stem cell
diabetes
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Summary:Stem cell therapy holds immense promise for the treatment of patients with diabetes mellitus. Research on the ability of human embryonic stem cells to differentiate into islet cells has defined the developmental stages and transcription factors involved in this process. However, the clinical applications of human embryonic stem cells are limited by ethical concerns, as well as the potential for teratoma formation. As a consequence, alternative forms of stem cell therapies, such as induced pluripotent stem cells, umbilical cord stem cells and bone marrow-derived mesenchymal stem cells, have become an area of intense study. Recent advances in stem cell therapy may turn this into a realistic treatment for diabetes in the near future.
ISSN:2230-8210
2230-9500
DOI:10.4103/2230-8210.104045