NCI Cancer Research Data Commons: Cloud-Based Analytic Resources

The NCI's Cloud Resources (CR) are the analytical components of the Cancer Research Data Commons (CRDC) ecosystem. This review describes how the three CRs (Broad Institute FireCloud, Institute for Systems Biology Cancer Gateway in the Cloud, and Seven Bridges Cancer Genomics Cloud) provide acce...

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Published inCancer research (Chicago, Ill.) Vol. 84; no. 9; pp. 1396 - 1403
Main Authors Pot, David, Worman, Zelia, Baumann, Alexander, Pathak, Shirish, Beck, Rowan, Beck, Erin, Thayer, Katherine, Davidsen, Tanja M, Kim, Erika, Davis-Dusenbery, Brandi, Otridge, John, Pihl, Todd, Barnholtz-Sloan, Jill S, Kerlavage, Anthony R
Format Journal Article
LanguageEnglish
Published United States American Association for Cancer Research 02.05.2024
Subjects
Biomedical Research
Cloud Computing
Computational Biology - methods
Computational Methods
Genomics - methods
Humans
Imaging
National Cancer Institute (U.S.)
Neoplasms - genetics
Reviews
United States
United States
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Summary:The NCI's Cloud Resources (CR) are the analytical components of the Cancer Research Data Commons (CRDC) ecosystem. This review describes how the three CRs (Broad Institute FireCloud, Institute for Systems Biology Cancer Gateway in the Cloud, and Seven Bridges Cancer Genomics Cloud) provide access and availability to large, cloud-hosted, multimodal cancer datasets, as well as offer tools and workspaces for performing data analysis where the data resides, without download or storage. In addition, users can upload their own data and tools into their workspaces, allowing researchers to create custom analysis workflows and integrate CRDC-hosted data with their own. See related articles by Brady et al., p. 1384, Wang et al., p. 1388, and Kim et al., p. 1404.
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Cancer Res 2024;84:1396–403
D. Pot, Z. Worman, and A. Baumann contributed equally to this article.
ISSN:0008-5472
1538-7445
DOI:10.1158/0008-5472.CAN-23-2657