Longitudinal personality change associated with cognitive decline in multiple sclerosis

We previously reported that personality and cognition were stable over 3 years in patients with multiple sclerosis (MS). This study examined whether a longer duration would reveal evidence of emerging personality dysfunction. The NEO Five-Factor Inventory and Brief International Cognitive Assessment...

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Bibliographic Details
Published inMultiple sclerosis p. 1352458517753720
Main Authors Roy, Shumita, Drake, Allison, Fuchs, Tom, Dwyer, Michael G, Zivadinov, Robert, Chapman, Benjamin P, Weinstock-Guttman, Bianca, Benedict, Ralph Hb
Format Journal Article
LanguageEnglish
Published England 01.12.2018
Subjects
Multiple sclerosis
personality
cognitive decline
longitudinal
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Summary:We previously reported that personality and cognition were stable over 3 years in patients with multiple sclerosis (MS). This study examined whether a longer duration would reveal evidence of emerging personality dysfunction. The NEO Five-Factor Inventory and Brief International Cognitive Assessment for MS was used to assess personality and cognition, respectively. Patients were classified as "Cog Stable" or "Cog Decline" based on cognitive deterioration over 5 years. Extraversion and Conscientiousness declined across pooled groups. Follow-up of a group by time interaction found that decline in these traits was more evident in the Cog Decline group, demonstrating a link between personality and cognitive change.
ISSN:1477-0970
DOI:10.1177/1352458517753720