Systemic vasculitis: one year in review 2023

Systemic vasculitides are heterogeneous disabling diseases characterised by chronic inflammation of the blood vessels potentially leading to tissue destruction and organ failure. The recent COVID-19 pandemic has had a significant impact on the epidemiology and management of patients with systemic va...

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Published inClinical and experimental rheumatology Vol. 41; no. 4; p. 765
Main Authors Moretti, Michele, Treppo, Elena, Monti, Sara, La Rocca, Gaetano, Del Frate, Giulia, Delvino, Paolo, Italiano, Nazzareno, Di Cianni, Federica, D'Alessandro, Francesco, Talarico, Rosaria, Ferro, Francesco, Quartuccio, Luca, Baldini, Chiara
Format Journal Article
LanguageEnglish
Published Italy 01.04.2023
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Summary:Systemic vasculitides are heterogeneous disabling diseases characterised by chronic inflammation of the blood vessels potentially leading to tissue destruction and organ failure. The recent COVID-19 pandemic has had a significant impact on the epidemiology and management of patients with systemic vasculitis. In parallel, new insights have been provided on systemic vasculitis pathogenetic mechanisms, possible new therapeutic targets, and newer glucocorticoid-sparing treatments with better safety profiles. As in the previous annual reviews of this series, in this review we will provide a critical digest of the most recent literature regarding pathophysiology, clinical manifestations, diagnostic tools and treatment options in small- and large-vessel vasculitis focusing on precision medicine in vasculitis.
ISSN:0392-856X
DOI:10.55563/clinexprheumatol/zf4daj