Heteroclitins R-S: new dibenzocylooctadiene lignans from Kadsura heteroclita

To study the dibenzocylooctadiene lignans from the stems of Kadsura heteroclita. Chromatographic separations of silica gel and semi-preparative HPLC were used. All of the structures were elucidated on the basis of spectroscopic analysis, including 2D-NMR and HR-MS techniques. Four dibenzocylooctadie...

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Published inChinese journal of natural medicines Vol. 12; no. 9; pp. 689 - 692
Main Authors CHEN, Min, LUO, You-Ping, ZOU, Yan-Lin, LANG, Ling-Hu, CHEN, Dao-Feng
Format Journal Article
LanguageEnglish
Published China Elsevier B.V 01.09.2014
Subjects
Dibenzocylooctadiene Lignan
Heteroclitins R-S
Kadsura - chemistry
Kadsura heteroclita
Lignans - chemistry
Lignans - isolation & purification
Molecular Structure
Plant Extracts - chemistry
Schisandraceae
Kadsura heteroclita
Heteroclitins R-S
Dibenzocylooctadiene Lignan
Schisandraceae
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Summary:To study the dibenzocylooctadiene lignans from the stems of Kadsura heteroclita. Chromatographic separations of silica gel and semi-preparative HPLC were used. All of the structures were elucidated on the basis of spectroscopic analysis, including 2D-NMR and HR-MS techniques. Four dibenzocylooctadiene lignans were isolated from K. heteroclita. Their structures were identified as heteroclitin R (1), heteroclitin S (2), gonisin O (3), and schisanlignone A (4). Heteroclitin R (1) and heteroclitin S (2) are new natural lignans.
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ISSN:1875-5364
1875-5364
DOI:10.1016/S1875-5364(14)60105-9