An intensive and glow-type chemiluminescence of luminol-embedded, guanosine-derived hydrogel

• Published in: Talanta (Oxford) Vol. 230; p. 122351
• Main Authors: Ye, Jing, Zhu, Liping, Yan, Mengxia, Xiao, Ting, Fan, Libing, Xue, Yu, Huang, Jianshe, Yang, Xiurong
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.08.2021
• Subjects: Chemiluminescence; Glow-type; Guanosine; Hydrogel; Luminol; Chemiluminescence; Hydrogel; Glow-type; Guanosine; Luminol
• ISSN: 0039-9140; 1873-3573
• DOI: 10.1016/j.talanta.2021.122351

In this paper, an intensive and glow-type chemiluminescence (CL) hydrogel was prepared by simultaneous incorporation of chemiluminescence reagent (luminol) and catalytic cofactor (hemin) into the scaffold of guanosine-derived hydrogel. The self-assembled hydrogel consisted of K+ stabilized hemin/G-quartet structures, showing significant enzyme-like activity to H2O2-mediated oxidation of luminol. After adding H2O2 into the hydrogel, blue light visible to naked eyes would come into being and last for over 8 h. The lasting-time CL emission of hydrogel was achieved due to a mechanism of slow-diffusion-controlled heterogeneous catalysis. Moreover, this self-assembled hydrogel performed a good response to H2O2 and the CL emission images could be recorded by smartphone. The hydrogel could remain excellent lifetime stability for months and the stable, enhanced and glow-type CL emission could improve the reliability and precision of CL detection, which has a promising application in cold light source and H2O2 detection of real biological samples. [Display omitted] •We proposed an intensive and glow-type chemiluminescence hydrogel based on the self-assembled guanosine-borate hydrogel.•The as-prepared chemiluminescence showed excellent lifetime stability and good response capacity to H2O2.•The hydrogel showed the promising applications in H2O2 detection, biological imaging, and cold sources.