Psychiatric comorbidities and quality of life in breast cancer patients undergoing radiation treatment: Risk and protective factors

• Published in: International journal of psychiatry in medicine Vol. 57; no. 1; pp. 53 - 68
• Main Authors: Shim, In Hee, Choi, Chul Won, Bae, Dong Sik, Ha, Su Hong, Kwon, Kyung A, Yoon, Tae In, Yi, On Vox
• Format: Journal Article
• Language: English
• Published: Los Angeles, CA SAGE Publications 01.01.2022; Sage Publications Ltd
• Subjects: Breast cancer; Breast Neoplasms - epidemiology; Breast Neoplasms - radiotherapy; Comorbidity; Female; Humans; Hypochondria; Protective Factors; Quality of life; Quality of Life - psychology; Radiation; Surveys and Questionnaires; distress; prevalence; risk factors; comorbidity; radiation therapy; breast cancer; quality of life; resilience; psychiatric disorders
• ISSN: 0091-2174; 1541-3527
• DOI: 10.1177/0091217421989144

Objective The primary goal was to evaluate the prevalence of psychiatric comorbidities and changes in psychological distress levels among breast cancer patients receiving radiotherapy (RT). The secondary goal was to determine risk and protective factors for psychiatric comorbidities of these patients. Methods From June 2018 to November 2019, patients were recruited from the hospital, Department of Psychiatry. Patients completed baseline surveys after seeing their radiation oncologist and prior to the first treatment, which was scheduled to take place within 7 days (visit 1, baseline); visit 2 occurred within 7 days after RT completion, and visit 3 occurred at 6 weeks after RT completion. A total of 99 patients participated in the study at visit 1; 56 patients completed the study through visit 3. Results Although changes in psychiatric comorbidities and overall quality of life were observed in patients with breast cancer prior to, during, and after RT, the differences were not significant among visits. Patients diagnosed with psychiatric comorbidities after RT had exhibited risk factors at previous visits, including preexisting psychiatric comorbidities, functional deterioration, and more severe symptoms related to breast cancer. Based on the results, the psychological characteristics of optimism and resilience can be considered as protective factors for psychiatric comorbidities. Conclusions The results suggest that early detection and follow-up of psychological distress and poor quality of life at the onset of RT are of paramount importance, and that psychosocial interventions to enhance protective factors (optimism and resilience) may be helpful.