Core-shell microparticles formed by the metal-organic framework CIM-80(Al) (Silica@CIM-80(Al)) as sorbent material in miniaturized dispersive solid-phase extraction

• Published in: Talanta (Oxford) Vol. 211; p. 120723
• Main Authors: Gutiérrez-Serpa, Adrián, Jiménez-Abizanda, Ana I., Jiménez-Moreno, Francisco, Pasán, Jorge, Pino, Verónica
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.05.2020
• Subjects: Core-shell microparticles; Metal-organic frameworks; Miniaturized dispersive solid-phase extraction; Novel sorbent material; Silica-based materials; Water analysis; Core-shell microparticles; Silica-based materials; Miniaturized dispersive solid-phase extraction; Water analysis; Metal-organic frameworks; Novel sorbent material
• ISSN: 0039-9140; 1873-3573
• DOI: 10.1016/j.talanta.2020.120723

Core-shell SiO2@CIM-80(Al) microspheres were synthesized, characterized, and used as novel sorbent in a dispersive miniaturized solid-phase extraction (D-μSPE) method for the determination of fourteen polycyclic aromatic hydrocarbons (PAHs) in wastewaters by ultra-high performance liquid chromatography coupled to a fluorescence detector (UHPLC-FD). A Doehlert experimental design permitted to optimize the main parameters affecting the microextraction procedure, intending the obtaining of a simple approach. Optimized extraction conditions include 13 mg of SiO2@CIM-80(Al) microparticles (~2 mg CIM-80(Al)), 2.5 min of extraction time, 0.125 mL of acetonitrile (ACN) as desorption solvent and 0.5 min of desorption time. The entire method showed adequate analytical performance with limits of detection down to 5 ng L−1, and inter-day precision lower than 14.1% for a concentration level of 0.5 μg L−1. The extraction capability of SiO2@CIM-80(Al) microspheres was compared to that obtained with commercially available silica microspheres and the neat MOF CIM-80(Al), demonstrating the advantages of the use of MOF core-shell sorbents in D-μSPE. SiO2@CIM-80(Al) as sorbent in D-μSPE followed by UHPLC-FD for determining 14 polycyclic aromatic hydrocarbons in wastewaters. [Display omitted] •Novel core-shell SiO2@CIM-80(Al) microspheres as sorbent material in microextraction.•The novel sorbent was used in miniaturized dispersive solid-phase extraction.•Adequate analytical performance of the sorbent in D-μ-SPE-UHPLC-FD for PAHs.•The performance was superior to neat CIM-80(Al) or silica, requiring lower MOF amounts.