Effect of acupressure at Sanyinjiao on albuminuria in patients with early diabetic nephropathy: A single-blind, randomized, controlled preliminary study

• Published in: Explore (New York, N.Y.) Vol. 16; no. 3; pp. 165 - 169
• Main Authors: Chuang, Shih-Ming, Lee, Chun-Chuan, Lo, Wan-Yu, Hsieh, Ching-Liang
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.05.2020
• Subjects: Acupressure; Albuminuria; Diabetic nephropathy; Sanyinjiao; Diabetic nephropathy; Albuminuria; Acupressure; Sanyinjiao
• ISSN: 1550-8307; 1878-7541
• DOI: 10.1016/j.explore.2019.09.001

Elevated urinary albumin excretion is a clinical manifestation of early-stage diabetic nephropathy (DN). To investigate effect of acupressure at Sanyinjiao on albuminuria in patients with early DN. Total included 53 patients with DN and albuminuria; 21 were assigned to the sham group without acupressure, and 32 were assigned to the experimental group with acupressure at Sanyinjiao (SP6) for 8weeks. The experimental group was divided into experiment A (acupressure <45 days) and experiment B (acupressure ≥45 days). The primary outcome measure was the urine albuminuria/creatinine ratio (UACR) or logarithmic transformed urine microalbumin creatinine ratio (log-UACR) changes, and the secondary outcome measures were the estimated glomerular filtration rate and hemoglobin A1c. The difference in UACR and log-UACR before and after the study was higher in the experiment B group than in the experiment A and sham groups. Acupressure at Sanyinjiao for 8 weeks may reduce albuminuria in patients with DN. However, this study was a preliminary design.