Incidence of invasive versus non-invasive carcinoma in comparing palpable and non-palpable solid breast lesions

A retrospective study was done of all patients with a suspicious mammographic breast lesion surgically biopsied in our institution within the last 5 years. Incidence of invasive versus non-invasive carcinoma and stage at presentation (according to TNM classification system) of palpable and non-palpa...

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Bibliographic Details
Published inActa chirurgica belgica Vol. 99; no. 5; p. 245
Main Authors Koentges, B, Van Eijkelenburg, P, Lamote, J, Ongena, K, Sacré, R
Format Journal Article
LanguageEnglish
Published England 01.10.1999
Subjects
Biopsy
Breast Neoplasms - diagnostic imaging
Breast Neoplasms - pathology
Female
Humans
Lymphatic Metastasis
Neoplasm Invasiveness
Neoplasm Staging
Predictive Value of Tests
Radiography
Retrospective Studies
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Summary:A retrospective study was done of all patients with a suspicious mammographic breast lesion surgically biopsied in our institution within the last 5 years. Incidence of invasive versus non-invasive carcinoma and stage at presentation (according to TNM classification system) of palpable and non-palpable lesions were compared. We found a significant difference of non-invasive carcinoma in non-palpable and palpable cancers: 42.2% versus 4.3% (p < 0.001). Patients with a non-palpable invasive carcinoma presenting at stage I (i.e. pT1 with no axillary metastasis) rated significantly higher compared to those with palpable lesions 51.8% versus 9.4% (p < 0.001). The true positive biopsy rate is 30%. As low as 10% has been considered reasonable. We have a total of 56% carcinomas detected on all biopsies: 30% for non-palpable lesions and 66.8% for palpable lesions. A more aggressive approach towards screening and biopsy of breast lesions might increase early detection of carcinoma and so improve survival.
ISSN:0001-5458
DOI:10.1080/00015458.1999.12098488