Evaluation of executive functions in children with rheumatic heart diseases

• Published in: Pediatric investigation Vol. 64; no. 1; pp. e15035 - n/a
• Main Authors: Aliyeva, Nigar, Yozgat, Yilmaz, Bakhshaliyev, Nijad, Afshord, Telli Zadehgan, Yozgat, Can Yilmaz, Kilicoglu, Ali Guven
• Format: Journal Article
• Language: English
• Published: Australia John Wiley & Sons, Inc 01.01.2022; Blackwell Publishing Ltd
• Subjects: acute rheumatic fever; Adolescent; Age; Alcohol use; Cardiology; Cardiovascular disease; Child; Children; Chorea; Cognitive ability; Cross-Sectional Studies; Executive Function; executive functions; Families & family life; Gender; Heart; Heart diseases; Humans; Inflammatory diseases; Intellectual disabilities; Interviews; Outpatient care facilities; Parents & parenting; Patients; Pediatrics; Pregnancy; Rheumatic Fever; Rheumatic heart disease; Rheumatic Heart Disease - complications; rheumatic heart diseases; Schizophrenia; Sociodemographics; Software; Statistical analysis; Sydenham's chorea; Young Adult; Young adults; United States > US; Wisconsin; rheumatic heart diseases; Sydenham's chorea; acute rheumatic fever; executive functions
• ISSN: 1328-8067; 2096-3726; 1442-200X; 2574-2272
• DOI: 10.1111/ped.15035

Background Acute rheumatic fever (ARF) is a multisystemic inflammatory disease in children and young adults. The most notable complications of ARF are rheumatic heart disease (RHD) and Sydenham's chorea (SC). There have been many reports about executive dysfunctions with children who have SC. “Executive function” is an umbrella term that is used to describe higher level cognitive functions. The aim of this study is to determine the executive functions of children with RHD. We evaluated executive functions in healthy children with the same sociodemographic characteristics as children with RHD. Methods Our study was designed as a cross‐sectional randomized study, including children with RHD aged between 12 and 18, and healthy controls. The difference between the patient and control group participants in terms of age, gender, education level, education level of the parents, family income level, and executive functions were investigated. Executive functions composed of Digit Sequence Test, Verbal Fluency Test, Trail‐Making Test, Stroop Test, Wisconsin Card Sorting Test. Results In our study, a total of 30 children with RHD were followed up at the pediatric cardiology outpatient clinic of Bezmialem Vakif University Hospital composed the patient group. The control group was made up of 30 healthy children of the same sex and age group as the patient group. The mean age of the case group was 14.73 ± 1.84 years. The Digit Span Test, Verbal Fluency Test, Trail‐Making Test, Wisconsin Card Sorting Test, and Stroop Test produced no statistically significant differences between the RHD patients and the controls. Conclusions No statistically significant difference was found between the RHD patients and control patients in any executive function test. It was suggested that executive dysfunction might not develop in RHD patients before developing SC.