ON THE SYNTHESIS AND REACTIVITY OF 4,10-DIHYDROBENZO[B]THIENO[2,3-E]THIEPIN-10-ACETIC ACID AND 5,10-DIHYDROBENZO[E]THIENO[3,2-B]THIEPIN-10-ACETIC ACID

A simple method to synthesize 4,10-dihydrobenzo[b]thieno[2,3-e]thiepin-10-acetic acid (8a) and 5,10-dihydrobenzo[e]thieno[3,2-b]thiepin-10-acetic acid (8b) starting from ketones 1a,b is described. The reactivity of the acid 8a has been investigated and some derivatives are reported.

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Bibliographic Details
Published inJournal of heterocyclic chemistry Vol. 29; no. 7; pp. 1789 - 1795
Main Authors DAICH, A, DECROIX, B
Format Journal Article
LanguageEnglish
Published TAMPA HETERO CORPORATION 01.12.1992
Subjects
Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
CYCLIZATION
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Summary:A simple method to synthesize 4,10-dihydrobenzo[b]thieno[2,3-e]thiepin-10-acetic acid (8a) and 5,10-dihydrobenzo[e]thieno[3,2-b]thiepin-10-acetic acid (8b) starting from ketones 1a,b is described. The reactivity of the acid 8a has been investigated and some derivatives are reported.
ISSN:0022-152X
DOI:10.1002/jhet.5570290720