A label-free colorimetric assay for detection of c-Myc mRNA based on peptide nucleic acid and silver nanoparticles

A label-free colorimetric protocol based on peptide nucleic acid/silver nanoparticles (PNA/AgNPs) has been initially proposed for specific recognition of mRNA. Making use of the controlled silver nanoparticles aggregation/dispersion by PNA/PNA–RNA complex, proto-oncogene c-Myc mRNA detection can be...

Full description

Saved in:
Bibliographic Details
Published inScience bulletin (Beijing) Vol. 61; no. 4; pp. 276 - 281
Main Authors Li, Xia, Song, Juan, Chen, Bao-Li, Wang, Bing, Li, Rui, Jiang, Hui-Min, Liu, Ji-Feng, Li, Chen-Zhong
Format Journal Article
LanguageEnglish
Published Beijing Elsevier B.V 01.02.2016
Science China Press
Subjects
c-Myc mRNA
Chemistry/Food Science
color
Colorimetric
colorimetry
Earth Sciences
Engineering
Humanities and Social Sciences
Life Sciences
messenger RNA
multidisciplinary
nanosilver
Peptide nucleic acid
Physics
proto-oncogenes
Science
Science (multidisciplinary)
Silver nanoparticles
Peptide nucleic acid
c-Myc mRNA
Silver nanoparticles
Colorimetric
比色法
mRNA
肽核酸
纳米银
Online AccessGet full text

Cover

Abstract A label-free colorimetric protocol based on peptide nucleic acid/silver nanoparticles (PNA/AgNPs) has been initially proposed for specific recognition of mRNA. Making use of the controlled silver nanoparticles aggregation/dispersion by PNA/PNA–RNA complex, proto-oncogene c-Myc mRNA detection can be achieved. Moreover, the PNA/AgNPs platform can undergo color change in response to target c-Myc mRNA with single-base-mismatch sensitivity, which could further help in visually identify single nucleotide differences in target genes.
AbstractList A label-free colorimetric protocol based on peptide nucleic acid/silver nanoparticles (PNA/AgNPs) has been initially proposed for specific recognition of mRNA. Making use of the controlled silver nanoparticles aggregation/dispersion by PNA/PNA–RNA complex, proto-oncogene c-Myc mRNA detection can be achieved. Moreover, the PNA/AgNPs platform can undergo color change in response to target c-Myc mRNA with single-base-mismatch sensitivity, which could further help in visually identify single nucleotide differences in target genes.
A label-free colorimetric protocol based on peptide nucleic acid/silver nanoparticles (PNA/AgNPs) has been initially proposed for specific recognition of mRNA. Making use of the controlled silver nanoparticles aggregation/dispersion by PNA/PNA–RNA complex, proto-oncogene c-Myc mRNA detection can be achieved. Moreover, the PNA/AgNPs platform can undergo color change in response to target c-Myc mRNA with single-base-mismatch sensitivity, which could further help in visually identify single nucleotide differences in target genes.
Author Chen, Bao-Li
Li, Chen-Zhong
Liu, Ji-Feng
Li, Rui
Wang, Bing
Jiang, Hui-Min
Song, Juan
Li, Xia
Author_xml – sequence: 1
  givenname: Xia
  surname: Li
  fullname: Li, Xia
  organization: Department of Chemistry, Liaocheng University, Liaocheng 252059, China
– sequence: 2
  givenname: Juan
  surname: Song
  fullname: Song, Juan
  organization: Department of Chemistry, Liaocheng University, Liaocheng 252059, China
– sequence: 3
  givenname: Bao-Li
  surname: Chen
  fullname: Chen, Bao-Li
  organization: Department of Chemistry, Liaocheng University, Liaocheng 252059, China
– sequence: 4
  givenname: Bing
  surname: Wang
  fullname: Wang, Bing
  organization: Department of Chemistry, Liaocheng University, Liaocheng 252059, China
– sequence: 5
  givenname: Rui
  surname: Li
  fullname: Li, Rui
  organization: Department of Chemistry, Liaocheng University, Liaocheng 252059, China
– sequence: 6
  givenname: Hui-Min
  surname: Jiang
  fullname: Jiang, Hui-Min
  organization: Department of Chemistry, Liaocheng University, Liaocheng 252059, China
– sequence: 7
  givenname: Ji-Feng
  surname: Liu
  fullname: Liu, Ji-Feng
  email: liujifeng111@gmail.com
  organization: Key Laboratory of Food Nutrition and Safety, Ministry of Education, Tianjin University of Science and Technology, Tianjin 300457, China
– sequence: 8
  givenname: Chen-Zhong
  surname: Li
  fullname: Li, Chen-Zhong
  email: lichenzhong@lcu.edu.cn
  organization: Department of Chemistry, Liaocheng University, Liaocheng 252059, China
BookMark eNp9kEtLAzEUhYMo-OoPcGX-QDSZybxwVYovqApq1yGT3JSUMSnJVOi_95YRl66Sm5xzuOc7J8chBiDkSvAbwXlzm4WQpWRc1AxnycojclbwrmJd0Yrjv3tTnpJZzhvOuZBdIXlzRtKcDrqHgbkEQE0cYvJfMCZvqM5Z76mLiVoYwYw-BhodNexlb-jX--uc9jqDpfi8he3oLdCwMwMcrMZbqoOl2Q_fkGjQIW51Gj1-50ty4vSQYfZ7XpDVw_3n4okt3x6fF_MlM2UtR2aNrNu6s5XhTWe0bLBFXXNwPVaWVsu-aXWrZSlc5Zq-7buqF3Vb9bYURYlALoiYck2KOSdwaovddNorwdWBm5q4KeR2mKUq0VNMnozasIakNnGXAq75r-l6MjkdlV4nn9Xqo0ABgm5rLjgq7iYFYN9vj7HZeAgGrE9IVtno_8n_Aez7jiU
CitedBy_id crossref_primary_10_1002_cjoc_202200368
crossref_primary_10_1016_j_colsurfb_2019_05_069
crossref_primary_10_1007_s12274_017_1490_x
crossref_primary_10_1007_s12274_022_4114_z
crossref_primary_10_1007_s11434_016_1165_0
crossref_primary_10_1007_s00604_024_06328_x
crossref_primary_10_1016_j_foodchem_2024_139442
crossref_primary_10_1007_s12274_016_1270_z
crossref_primary_10_1016_j_biosx_2022_100259
crossref_primary_10_3390_nano6100190
crossref_primary_10_3390_catal11050638
crossref_primary_10_1016_j_bios_2021_113581
crossref_primary_10_3389_fnano_2022_885803
Cites_doi 10.1021/ja011342n
10.1016/j.aca.2014.04.034
10.1039/cs9972600073
10.1039/c2cc35008d
10.1007/s11434-014-0709-4
10.1021/ac301787x
10.1021/pr200584y
10.1021/ac071198+
10.1021/ac101193e
10.1021/mp200177z
10.1016/j.bios.2012.05.039
10.1007/s11434-015-0801-4
10.1021/nn9005768
10.1016/j.aca.2013.06.037
10.1021/nl071108g
10.1021/ac401983w
10.1021/ja0295220
10.1021/am500534g
10.1351/pac199870010105
10.1021/ac3009912
10.1039/c3ra43729a
10.1007/s11434-015-0814-z
ContentType Journal Article
Copyright 2016 Science China Press
Science China Press and Springer-Verlag Berlin Heidelberg 2016
Copyright_xml – notice: 2016 Science China Press
– notice: Science China Press and Springer-Verlag Berlin Heidelberg 2016
DBID FBQ
AAYXX
CITATION
DOI 10.1007/s11434-016-1004-3
DatabaseName AGRIS
CrossRef
DatabaseTitle CrossRef
DatabaseTitleList


Database_xml – sequence: 1
  dbid: FBQ
  name: AGRIS
  url: http://www.fao.org/agris/Centre.asp?Menu_1ID=DB&Menu_2ID=DB1&Language=EN&Content=http://www.fao.org/agris/search?Language=EN
  sourceTypes: Publisher
DeliveryMethod fulltext_linktorsrc
Discipline Sciences (General)
Engineering
Physics
DocumentTitle_FL 利用肽核酸和纳米银免标记比色检测原癌基因c-Myc mRNA
EISSN 2095-9281
EndPage 281
ExternalDocumentID 10_1007_s11434_016_1004_3
US201600086010
S2095927316301840
GroupedDBID --M
0R~
4.4
5VR
AACTN
AAEDT
AAEDW
AAIAL
AAIAV
AAJKR
AAKOC
AALRI
AANXM
AAOAW
AARTL
AAXUO
AAYIU
AAYQN
AAYTO
ABBBX
ABJNI
ABJOX
ABMAC
ABQEM
ABQYD
ABTEG
ABTHY
ABTMW
ABUDA
ABYKQ
ACBXY
ACDAQ
ACGFS
ACIWK
ACKNC
ACPRK
ACRLP
ADBBV
ADINQ
ADKPE
ADRFC
AEBSH
AEGNC
AEHWI
AEJHL
AENEX
AEOHA
AEPYU
AFKWA
AFLOW
AFNRJ
AFRAH
AFTJW
AFUIB
AFXIZ
AFZHZ
AFZKB
AGJBK
AGQMX
AGUBO
AGWZB
AGYKE
AHAVH
AHBYD
AHJVU
AHSBF
AIEXJ
AIIXL
AIKHN
AITUG
AJBFU
AJBLW
AJSZI
ALMA_UNASSIGNED_HOLDINGS
AMFUW
AMKLP
AMRAJ
ASPBG
ATOGT
AUKKA
AVWKF
AXJTR
AZFZN
BGNMA
BJAXD
BKOJK
CCEZO
CCVFK
CHBEP
CSCUP
EBS
EFJIC
EFLBG
EJD
FA0
FDB
FIRID
FRRFC
FYGXN
HG6
HX~
IXD
KOM
KOV
M41
M4Y
NU0
O9-
ROL
RSV
SOJ
SPC
SPCBC
SSE
SSK
SST
SSU
SSZ
T5K
TCJ
TGP
UG4
~G-
ABPIF
ABPTK
FBQ
-SA
-S~
5XA
5XB
AAQFI
AAXDM
AAXKI
AAYXX
ADVLN
AFBBN
AFJKZ
AKRWK
CAJEA
CITATION
CJPJV
H13
Q--
U1G
U5K
ID FETCH-LOGICAL-c364t-dc46869d5c079ca47209660efb0074da4b78a8a431f5f7b8b95b1685bd3123143
IEDL.DBID AGYKE
ISSN 2095-9273
IngestDate Thu Sep 26 18:41:10 EDT 2024
Sat Dec 16 12:01:03 EST 2023
Wed Dec 27 19:01:28 EST 2023
Fri Feb 23 02:33:51 EST 2024
IsPeerReviewed true
IsScholarly true
Issue 4
Keywords Peptide nucleic acid
c-Myc mRNA
Silver nanoparticles
Colorimetric
比色法
mRNA
肽核酸
纳米银
Language English
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c364t-dc46869d5c079ca47209660efb0074da4b78a8a431f5f7b8b95b1685bd3123143
Notes http://dx.doi.org/10.1007/s11434-016-1004-3
PageCount 6
ParticipantIDs crossref_primary_10_1007_s11434_016_1004_3
springer_journals_10_1007_s11434_016_1004_3
fao_agris_US201600086010
elsevier_sciencedirect_doi_10_1007_s11434_016_1004_3
PublicationCentury 2000
PublicationDate 2016-02-01
PublicationDateYYYYMMDD 2016-02-01
PublicationDate_xml – month: 02
  year: 2016
  text: 2016-02-01
  day: 01
PublicationDecade 2010
PublicationPlace Beijing
PublicationPlace_xml – name: Beijing
PublicationTitle Science bulletin (Beijing)
PublicationTitleAbbrev Sci. Bull
PublicationYear 2016
Publisher Elsevier B.V
Science China Press
Publisher_xml – name: Elsevier B.V
– name: Science China Press
References Valentini, Pompa (bib7) 2013; 3
Li, Sun, Zhong (bib12) 2010; 82
Nielsen (bib16) 1998; 70
Huang, Chiu, Li (bib1) 2014; 6
Wu, Qian, Xu (bib4) 2012; 84
Cao, Wang, Fan (bib8) 2015; 60
Cao, Jin, Mirkin (bib6) 2001; 123
Zhang, Mark, Liu (bib10) 2012; 48
Komiyama, Ye, Liang (bib19) 2003; 125
Wu, Kwak, Agarwal (bib5) 2013; 85
Duy, Smith, Collins (bib20) 2014; 52
Stephen, Yeung, Hsing (bib3) 2008; 80
Zhao, Hu (bib9) 2015; 60
Nielsen, Haaima (bib17) 1997; 26
Li, Chen, Wei (bib13) 2012; 84
Lee, Lytton-Jean, Hurst (bib14) 2007; 7
Pocsfalvi, Votta, Vincenzo (bib21) 2011; 10
Li, Zhu, Dong (bib11) 2014; 829
Joshi, Chindera, Singh (bib18) 2013; 795
Kauraniemi, Bärlund, Monni (bib2) 2001; 61
Su, Kanjanawarut (bib15) 2009; 3
Mehndiratta, Palanichamy, Bhagat (bib22) 2011; 8
Joshi, Chindera, Singh (CR18) 2013; 795
Nielsen (CR16) 1998; 70
Huang, Chiu, Li (CR1) 2014; 6
Valentini, Pompa (CR7) 2013; 3
Li, Zhu, Dong (CR11) 2014; 829
Li, Sun, Zhong (CR12) 2010; 82
Komiyama, Ye, Liang (CR19) 2003; 125
Pocsfalvi, Votta, Vincenzo (CR21) 2011; 10
Wu, Qian, Xu (CR4) 2012; 84
Stephen, Yeung, Hsing (CR3) 2008; 80
Wu, Kwak, Agarwal (CR5) 2013; 85
Zhang, Mark, Liu (CR10) 2012; 48
Cao, Wang, Fan (CR8) 2015; 60
Lee, Lytton-Jean, Hurst (CR14) 2007; 7
Su, Kanjanawarut (CR15) 2009; 3
Li, Chen, Wei (CR13) 2012; 84
Nielsen, Haaima (CR17) 1997; 26
Mehndiratta, Palanichamy, Bhagat (CR22) 2011; 8
Duy, Smith, Collins (CR20) 2014; 52
Cao, Jin, Mirkin (CR6) 2001; 123
Zhao, Hu (CR9) 2015; 60
Kauraniemi, Bärlund, Monni (CR2) 2001; 61
Cao (10.1007/s11434-016-1004-3_bib8) 2015; 60
Zhao (10.1007/s11434-016-1004-3_bib9) 2015; 60
Kauraniemi (10.1007/s11434-016-1004-3_bib2) 2001; 61
Pocsfalvi (10.1007/s11434-016-1004-3_bib21) 2011; 10
Valentini (10.1007/s11434-016-1004-3_bib7) 2013; 3
Joshi (10.1007/s11434-016-1004-3_bib18) 2013; 795
Komiyama (10.1007/s11434-016-1004-3_bib19) 2003; 125
Li (10.1007/s11434-016-1004-3_bib11) 2014; 829
Li (10.1007/s11434-016-1004-3_bib12) 2010; 82
Wu (10.1007/s11434-016-1004-3_bib5) 2013; 85
Duy (10.1007/s11434-016-1004-3_bib20) 2014; 52
Li (10.1007/s11434-016-1004-3_bib13) 2012; 84
Nielsen (10.1007/s11434-016-1004-3_bib17) 1997; 26
Huang (10.1007/s11434-016-1004-3_bib1) 2014; 6
Lee (10.1007/s11434-016-1004-3_bib14) 2007; 7
Wu (10.1007/s11434-016-1004-3_bib4) 2012; 84
Zhang (10.1007/s11434-016-1004-3_bib10) 2012; 48
Mehndiratta (10.1007/s11434-016-1004-3_bib22) 2011; 8
Stephen (10.1007/s11434-016-1004-3_bib3) 2008; 80
Su (10.1007/s11434-016-1004-3_bib15) 2009; 3
Cao (10.1007/s11434-016-1004-3_bib6) 2001; 123
Nielsen (10.1007/s11434-016-1004-3_bib16) 1998; 70
References_xml – volume: 60
  start-page: 279
  year: 2015
  end-page: 280
  ident: bib9
  article-title: Cancer therapy may get a boost from gold nanorods
  publication-title: Sci Bull
  contributor:
    fullname: Hu
– volume: 3
  start-page: 2751
  year: 2009
  end-page: 2759
  ident: bib15
  article-title: Control of metal nanoparticles aggregation and dispersion by PNA and PNA-DNA complexes, and its application for colorimetric DNA detection
  publication-title: ACS Nano
  contributor:
    fullname: Kanjanawarut
– volume: 6
  start-page: 21780
  year: 2014
  end-page: 21787
  ident: bib1
  article-title: Detection of microRNA in tumor cells using exonuclease III and graphene oxide regulated signal amplification
  publication-title: ACS Appl Mater Interfaces
  contributor:
    fullname: Li
– volume: 123
  start-page: 7961
  year: 2001
  end-page: 7962
  ident: bib6
  article-title: DNA-modified core-shell Ag/Au nanoparticles
  publication-title: J Am Chem Soc
  contributor:
    fullname: Mirkin
– volume: 48
  start-page: 10114
  year: 2012
  end-page: 10116
  ident: bib10
  article-title: Fast pH-assisted functionalization of silver nanoparticles with monothiolated DNA
  publication-title: Chem Commun
  contributor:
    fullname: Liu
– volume: 84
  start-page: 8656
  year: 2012
  end-page: 8662
  ident: bib13
  article-title: Highly sensitive detection of proteins based on metal-enhanced fluorescence with novel silver nanostructures
  publication-title: Anal Chem
  contributor:
    fullname: Wei
– volume: 795
  start-page: 1
  year: 2013
  end-page: 7
  ident: bib18
  article-title: Rapid label-free visual assay for the detection and quantification of viral RNA using peptide nucleic acid and gold nanoparticles
  publication-title: Anal Chim Acta
  contributor:
    fullname: Singh
– volume: 84
  start-page: 5407
  year: 2012
  end-page: 5414
  ident: bib4
  article-title: Sensitive electrochemiluminescence detection of
  publication-title: Anal Chem
  contributor:
    fullname: Xu
– volume: 3
  start-page: 19181
  year: 2013
  end-page: 19190
  ident: bib7
  article-title: Gold nanoparticles for naked-eye DNA detection: smart designs for sensitive assays
  publication-title: RSC Adv
  contributor:
    fullname: Pompa
– volume: 85
  start-page: 11265
  year: 2013
  end-page: 11274
  ident: bib5
  article-title: Detection of extracellular RNAs in cancer and viral infection via tethered cationic lipoplex nanoparticles containing molecular beacons
  publication-title: Anal Chem
  contributor:
    fullname: Agarwal
– volume: 60
  start-page: 1101
  year: 2015
  end-page: 1107
  ident: bib8
  article-title: Fabrication of super-stable gold nanorod-carbon nanocapsule as a molecule loading material
  publication-title: Sci Bull
  contributor:
    fullname: Fan
– volume: 26
  start-page: 73
  year: 1997
  end-page: 78
  ident: bib17
  article-title: Peptide nucleic acid (PNA), A DNA mimic with a pseudopeptide backbone
  publication-title: Chem Soc Rev
  contributor:
    fullname: Haaima
– volume: 125
  start-page: 3758
  year: 2003
  end-page: 3762
  ident: bib19
  article-title: PNA for one-base differentiating protection of DNA from nuclease and its use for SNPs detection
  publication-title: J Am Chem Soc
  contributor:
    fullname: Liang
– volume: 80
  start-page: 363
  year: 2008
  end-page: 368
  ident: bib3
  article-title: Electrochemistry based real-time PCR on a microchip
  publication-title: Anal Chem
  contributor:
    fullname: Hsing
– volume: 61
  start-page: 8235
  year: 2001
  end-page: 8240
  ident: bib2
  article-title: New amplified and highly expressed genes discovered in the ERBB2 applicant in breast cancer by cDNA microarrays
  publication-title: Cancer Res
  contributor:
    fullname: Monni
– volume: 70
  start-page: 105
  year: 1998
  end-page: 110
  ident: bib16
  article-title: Structural and biological properties of peptide nucleic acid (PNA)
  publication-title: Pure Appl Chem
  contributor:
    fullname: Nielsen
– volume: 7
  start-page: 2112
  year: 2007
  end-page: 2115
  ident: bib14
  article-title: Silver nanoparticle-oligonucleotide conjugates based on DNA with triple cyclic disulfide moieties
  publication-title: Nano Lett
  contributor:
    fullname: Hurst
– volume: 10
  start-page: 5326
  year: 2011
  end-page: 5337
  ident: bib21
  article-title: Analysis of secretome changes uncovers an autocrine/paracrine component in the modulation of cell proliferation and motility by
  publication-title: J Proteome Res
  contributor:
    fullname: Vincenzo
– volume: 829
  start-page: 48
  year: 2014
  end-page: 53
  ident: bib11
  article-title: Fast functionalization of silver decahedral nanoparticles with aptamers for colorimetric detection of human platelet-derived growth factor-BB
  publication-title: Anal Chim Acta
  contributor:
    fullname: Dong
– volume: 82
  start-page: 5477
  year: 2010
  end-page: 5483
  ident: bib12
  article-title: Ultrasensitive electrochemical detection for DNA arrays based on silver nanoparticle aggregates
  publication-title: Anal Chem
  contributor:
    fullname: Zhong
– volume: 52
  start-page: 433
  year: 2014
  end-page: 437
  ident: bib20
  article-title: A field deployable colorimetric bioassay for the rapid and specific detection of ribosomal RNA
  publication-title: Biosens Bioelectron
  contributor:
    fullname: Collins
– volume: 8
  start-page: 2302
  year: 2011
  end-page: 2309
  ident: bib22
  article-title: CpG hypermethylation of the
  publication-title: Mol Pharm
  contributor:
    fullname: Bhagat
– volume: 123
  start-page: 7961
  year: 2001
  end-page: 7962
  ident: CR6
  article-title: DNA-modified core-shell Ag/Au nanoparticles
  publication-title: J Am Chem Soc
  doi: 10.1021/ja011342n
  contributor:
    fullname: Mirkin
– volume: 829
  start-page: 48
  year: 2014
  end-page: 53
  ident: CR11
  article-title: Fast functionalization of silver decahedral nanoparticles with aptamers for colorimetric detection of human platelet-derived growth factor-BB
  publication-title: Anal Chim Acta
  doi: 10.1016/j.aca.2014.04.034
  contributor:
    fullname: Dong
– volume: 26
  start-page: 73
  year: 1997
  end-page: 78
  ident: CR17
  article-title: Peptide nucleic acid (PNA), A DNA mimic with a pseudopeptide backbone
  publication-title: Chem Soc Rev
  doi: 10.1039/cs9972600073
  contributor:
    fullname: Haaima
– volume: 48
  start-page: 10114
  year: 2012
  end-page: 10116
  ident: CR10
  article-title: Fast pH-assisted functionalization of silver nanoparticles with monothiolated DNA
  publication-title: Chem Commun
  doi: 10.1039/c2cc35008d
  contributor:
    fullname: Liu
– volume: 60
  start-page: 279
  year: 2015
  end-page: 280
  ident: CR9
  article-title: Cancer therapy may get a boost from gold nanorods
  publication-title: Sci Bull
  doi: 10.1007/s11434-014-0709-4
  contributor:
    fullname: Hu
– volume: 84
  start-page: 8656
  year: 2012
  end-page: 8662
  ident: CR13
  article-title: Highly sensitive detection of proteins based on metal-enhanced fluorescence with novel silver nanostructures
  publication-title: Anal Chem
  doi: 10.1021/ac301787x
  contributor:
    fullname: Wei
– volume: 10
  start-page: 5326
  year: 2011
  end-page: 5337
  ident: CR21
  article-title: Analysis of secretome changes uncovers an autocrine/paracrine component in the modulation of cell proliferation and motility by
  publication-title: J Proteome Res
  doi: 10.1021/pr200584y
  contributor:
    fullname: Vincenzo
– volume: 61
  start-page: 8235
  year: 2001
  end-page: 8240
  ident: CR2
  article-title: New amplified and highly expressed genes discovered in the ERBB2 applicant in breast cancer by cDNA microarrays
  publication-title: Cancer Res
  contributor:
    fullname: Monni
– volume: 80
  start-page: 363
  year: 2008
  end-page: 368
  ident: CR3
  article-title: Electrochemistry based real-time PCR on a microchip
  publication-title: Anal Chem
  doi: 10.1021/ac071198+
  contributor:
    fullname: Hsing
– volume: 82
  start-page: 5477
  year: 2010
  end-page: 5483
  ident: CR12
  article-title: Ultrasensitive electrochemical detection for DNA arrays based on silver nanoparticle aggregates
  publication-title: Anal Chem
  doi: 10.1021/ac101193e
  contributor:
    fullname: Zhong
– volume: 8
  start-page: 2302
  year: 2011
  end-page: 2309
  ident: CR22
  article-title: CpG hypermethylation of the promoter by dsRNA results in growth suppression
  publication-title: Mol Pharm
  doi: 10.1021/mp200177z
  contributor:
    fullname: Bhagat
– volume: 52
  start-page: 433
  year: 2014
  end-page: 437
  ident: CR20
  article-title: A field deployable colorimetric bioassay for the rapid and specific detection of ribosomal RNA
  publication-title: Biosens Bioelectron
  doi: 10.1016/j.bios.2012.05.039
  contributor:
    fullname: Collins
– volume: 60
  start-page: 1101
  year: 2015
  end-page: 1107
  ident: CR8
  article-title: Fabrication of superstable gold nanorod–carbon nanocapsule as a molecule loading material
  publication-title: Sci Bull
  doi: 10.1007/s11434-015-0801-4
  contributor:
    fullname: Fan
– volume: 3
  start-page: 2751
  year: 2009
  end-page: 2759
  ident: CR15
  article-title: Control of metal nanoparticles aggregation and dispersion by PNA and PNA-DNA complexes, and its application for colorimetric DNA detection
  publication-title: ACS Nano
  doi: 10.1021/nn9005768
  contributor:
    fullname: Kanjanawarut
– volume: 795
  start-page: 1
  year: 2013
  end-page: 7
  ident: CR18
  article-title: Rapid label-free visual assay for the detection and quantification of viral RNA using peptide nucleic acid and gold nanoparticles
  publication-title: Anal Chim Acta
  doi: 10.1016/j.aca.2013.06.037
  contributor:
    fullname: Singh
– volume: 7
  start-page: 2112
  year: 2007
  end-page: 2115
  ident: CR14
  article-title: Silver nanoparticle-oligonucleotide conjugates based on DNA with triple cyclic disulfide moieties
  publication-title: Nano Lett
  doi: 10.1021/nl071108g
  contributor:
    fullname: Hurst
– volume: 85
  start-page: 11265
  year: 2013
  end-page: 11274
  ident: CR5
  article-title: Detection of extracellular RNAs in cancer and viral infection via tethered cationic lipoplex nanoparticles containing molecular beacons
  publication-title: Anal Chem
  doi: 10.1021/ac401983w
  contributor:
    fullname: Agarwal
– volume: 125
  start-page: 3758
  year: 2003
  end-page: 3762
  ident: CR19
  article-title: PNA for one-base differentiating protection of DNA from nuclease and its use for SNPs detection
  publication-title: J Am Chem Soc
  doi: 10.1021/ja0295220
  contributor:
    fullname: Liang
– volume: 6
  start-page: 21780
  year: 2014
  end-page: 21787
  ident: CR1
  article-title: Detection of microRNA in tumor cells using exonuclease III and graphene oxide regulated signal amplification
  publication-title: ACS Appl Mater Interfaces
  doi: 10.1021/am500534g
  contributor:
    fullname: Li
– volume: 70
  start-page: 105
  year: 1998
  end-page: 110
  ident: CR16
  article-title: Structural and biological properties of peptide nucleic acid (PNA)
  publication-title: Pure Appl Chem
  doi: 10.1351/pac199870010105
  contributor:
    fullname: Nielsen
– volume: 84
  start-page: 5407
  year: 2012
  end-page: 5414
  ident: CR4
  article-title: Sensitive electrochemiluminescence detection of mRNA in breast cancer cells on a wireless bipolar electrode
  publication-title: Anal Chem
  doi: 10.1021/ac3009912
  contributor:
    fullname: Xu
– volume: 3
  start-page: 19181
  year: 2013
  end-page: 19190
  ident: CR7
  article-title: Gold nanoparticles for naked-eye DNA detection: smart designs for sensitive assays
  publication-title: RSC Adv
  doi: 10.1039/c3ra43729a
  contributor:
    fullname: Pompa
– volume: 6
  start-page: 21780
  year: 2014
  ident: 10.1007/s11434-016-1004-3_bib1
  article-title: Detection of microRNA in tumor cells using exonuclease III and graphene oxide regulated signal amplification
  publication-title: ACS Appl Mater Interfaces
  doi: 10.1021/am500534g
  contributor:
    fullname: Huang
– volume: 84
  start-page: 5407
  year: 2012
  ident: 10.1007/s11434-016-1004-3_bib4
  article-title: Sensitive electrochemiluminescence detection of c-Myc mRNA in breast cancer cells on a wireless bipolar electrode
  publication-title: Anal Chem
  doi: 10.1021/ac3009912
  contributor:
    fullname: Wu
– volume: 10
  start-page: 5326
  year: 2011
  ident: 10.1007/s11434-016-1004-3_bib21
  article-title: Analysis of secretome changes uncovers an autocrine/paracrine component in the modulation of cell proliferation and motility by c-Myc
  publication-title: J Proteome Res
  doi: 10.1021/pr200584y
  contributor:
    fullname: Pocsfalvi
– volume: 52
  start-page: 433
  year: 2014
  ident: 10.1007/s11434-016-1004-3_bib20
  article-title: A field deployable colorimetric bioassay for the rapid and specific detection of ribosomal RNA
  publication-title: Biosens Bioelectron
  doi: 10.1016/j.bios.2012.05.039
  contributor:
    fullname: Duy
– volume: 795
  start-page: 1
  year: 2013
  ident: 10.1007/s11434-016-1004-3_bib18
  article-title: Rapid label-free visual assay for the detection and quantification of viral RNA using peptide nucleic acid and gold nanoparticles
  publication-title: Anal Chim Acta
  doi: 10.1016/j.aca.2013.06.037
  contributor:
    fullname: Joshi
– volume: 61
  start-page: 8235
  year: 2001
  ident: 10.1007/s11434-016-1004-3_bib2
  article-title: New amplified and highly expressed genes discovered in the ERBB2 applicant in breast cancer by cDNA microarrays
  publication-title: Cancer Res
  contributor:
    fullname: Kauraniemi
– volume: 80
  start-page: 363
  year: 2008
  ident: 10.1007/s11434-016-1004-3_bib3
  article-title: Electrochemistry based real-time PCR on a microchip
  publication-title: Anal Chem
  doi: 10.1021/ac071198+
  contributor:
    fullname: Stephen
– volume: 123
  start-page: 7961
  year: 2001
  ident: 10.1007/s11434-016-1004-3_bib6
  article-title: DNA-modified core-shell Ag/Au nanoparticles
  publication-title: J Am Chem Soc
  doi: 10.1021/ja011342n
  contributor:
    fullname: Cao
– volume: 60
  start-page: 1101
  year: 2015
  ident: 10.1007/s11434-016-1004-3_bib8
  article-title: Fabrication of super-stable gold nanorod-carbon nanocapsule as a molecule loading material
  publication-title: Sci Bull
  doi: 10.1007/s11434-015-0814-z
  contributor:
    fullname: Cao
– volume: 48
  start-page: 10114
  year: 2012
  ident: 10.1007/s11434-016-1004-3_bib10
  article-title: Fast pH-assisted functionalization of silver nanoparticles with monothiolated DNA
  publication-title: Chem Commun
  doi: 10.1039/c2cc35008d
  contributor:
    fullname: Zhang
– volume: 125
  start-page: 3758
  year: 2003
  ident: 10.1007/s11434-016-1004-3_bib19
  article-title: PNA for one-base differentiating protection of DNA from nuclease and its use for SNPs detection
  publication-title: J Am Chem Soc
  doi: 10.1021/ja0295220
  contributor:
    fullname: Komiyama
– volume: 7
  start-page: 2112
  year: 2007
  ident: 10.1007/s11434-016-1004-3_bib14
  article-title: Silver nanoparticle-oligonucleotide conjugates based on DNA with triple cyclic disulfide moieties
  publication-title: Nano Lett
  doi: 10.1021/nl071108g
  contributor:
    fullname: Lee
– volume: 84
  start-page: 8656
  year: 2012
  ident: 10.1007/s11434-016-1004-3_bib13
  article-title: Highly sensitive detection of proteins based on metal-enhanced fluorescence with novel silver nanostructures
  publication-title: Anal Chem
  doi: 10.1021/ac301787x
  contributor:
    fullname: Li
– volume: 3
  start-page: 19181
  year: 2013
  ident: 10.1007/s11434-016-1004-3_bib7
  article-title: Gold nanoparticles for naked-eye DNA detection: smart designs for sensitive assays
  publication-title: RSC Adv
  doi: 10.1039/c3ra43729a
  contributor:
    fullname: Valentini
– volume: 3
  start-page: 2751
  year: 2009
  ident: 10.1007/s11434-016-1004-3_bib15
  article-title: Control of metal nanoparticles aggregation and dispersion by PNA and PNA-DNA complexes, and its application for colorimetric DNA detection
  publication-title: ACS Nano
  doi: 10.1021/nn9005768
  contributor:
    fullname: Su
– volume: 829
  start-page: 48
  year: 2014
  ident: 10.1007/s11434-016-1004-3_bib11
  article-title: Fast functionalization of silver decahedral nanoparticles with aptamers for colorimetric detection of human platelet-derived growth factor-BB
  publication-title: Anal Chim Acta
  doi: 10.1016/j.aca.2014.04.034
  contributor:
    fullname: Li
– volume: 70
  start-page: 105
  year: 1998
  ident: 10.1007/s11434-016-1004-3_bib16
  article-title: Structural and biological properties of peptide nucleic acid (PNA)
  publication-title: Pure Appl Chem
  doi: 10.1351/pac199870010105
  contributor:
    fullname: Nielsen
– volume: 85
  start-page: 11265
  year: 2013
  ident: 10.1007/s11434-016-1004-3_bib5
  article-title: Detection of extracellular RNAs in cancer and viral infection via tethered cationic lipoplex nanoparticles containing molecular beacons
  publication-title: Anal Chem
  doi: 10.1021/ac401983w
  contributor:
    fullname: Wu
– volume: 82
  start-page: 5477
  year: 2010
  ident: 10.1007/s11434-016-1004-3_bib12
  article-title: Ultrasensitive electrochemical detection for DNA arrays based on silver nanoparticle aggregates
  publication-title: Anal Chem
  doi: 10.1021/ac101193e
  contributor:
    fullname: Li
– volume: 26
  start-page: 73
  year: 1997
  ident: 10.1007/s11434-016-1004-3_bib17
  article-title: Peptide nucleic acid (PNA), A DNA mimic with a pseudopeptide backbone
  publication-title: Chem Soc Rev
  doi: 10.1039/cs9972600073
  contributor:
    fullname: Nielsen
– volume: 8
  start-page: 2302
  year: 2011
  ident: 10.1007/s11434-016-1004-3_bib22
  article-title: CpG hypermethylation of the c-Myc promoter by dsRNA results in growth suppression
  publication-title: Mol Pharm
  doi: 10.1021/mp200177z
  contributor:
    fullname: Mehndiratta
– volume: 60
  start-page: 279
  year: 2015
  ident: 10.1007/s11434-016-1004-3_bib9
  article-title: Cancer therapy may get a boost from gold nanorods
  publication-title: Sci Bull
  doi: 10.1007/s11434-014-0709-4
  contributor:
    fullname: Zhao
SSID ssj0001492407
Score 2.2375312
Snippet A label-free colorimetric protocol based on peptide nucleic acid/silver nanoparticles (PNA/AgNPs) has been initially proposed for specific recognition of mRNA....
SourceID crossref
springer
fao
elsevier
SourceType Aggregation Database
Publisher
StartPage 276
SubjectTerms c-Myc mRNA
Chemistry/Food Science
color
Colorimetric
colorimetry
Earth Sciences
Engineering
Humanities and Social Sciences
Life Sciences
messenger RNA
multidisciplinary
nanosilver
Peptide nucleic acid
Physics
proto-oncogenes
Science
Science (multidisciplinary)
Silver nanoparticles
SummonAdditionalLinks – databaseName: ScienceDirect Journal Collection
  dbid: AIKHN
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Li9swEB52s5deSrcPNn0xhx76QMSOZck-hqVL2tIc2gb2JvQsgdYJSXrYf98ZW2YpZXvoVSDLzIzmIX36BuCVb4rGkh0Im2QtpHZBWK8rYW2o_TyplAaU70ot1_LjdX19ApfjWxiGVWbfP_j03lvnkVmW5my32cy-zvkIa86dl8hIqU45hbP-kmgCZ4sPn5ar26MW2XLdwm3mCu5MSHPG-83-ER2lDIzEUILZ00R1V4Q6TXb7131pH4auHsD9nD_iYvjFcziJ3UM4zzv0gK8zjfSbR7BfIGk4_hBpHyMyOTUz-TMhP1LCbG-Q0lUM8dhjsTrcJvTi843Hn19WC-TgFpCGd4x6CRE75j3mqX4T0HYBDxvGVGNnOyq7M7ruMayv3n-7XIrcYUH4SsmjCF6qRrWklkK33kpNAlKqiMlxahGsdJo0aSnJSHXSrnFt7UrV1C5UFPFIbk9g0m27eAEYy-B1U0QbUyW91o4KEduWvgxNK2urp_B2lKrZDUQa5pYymVVgGGzGKjDVFOQod_OHNRhy9P-adkE6MvY7-UezJgMpVV-zUc05hXej4kzepYe7P_T0_9Z_Bvd4zQHU_Rwmx_2v-IJylqN7mW3yN-_d4pY
  priority: 102
  providerName: Elsevier
Title A label-free colorimetric assay for detection of c-Myc mRNA based on peptide nucleic acid and silver nanoparticles
URI https://dx.doi.org/10.1007/s11434-016-1004-3
https://link.springer.com/article/10.1007/s11434-016-1004-3
Volume 61
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV1Lb9QwEB61WyHBodAF1C0P-cCBh7zKbhw7Oa4QZWHFHgoryinys6oK3mqTHsqvZyYPWqkUqadIUewononnG_vzNwCvbJ7kGv2A6yAyLpRxXFuVcq1dZqdBhtCyfJdyvhKfj7PjLZj-XbqIZ-N-R7KZqK_OumFkJ8KE5CRyxtNt2KFzp9kAdmYffyyurayIgtIUqiqXUCFCDND9dua_-rktIG0Hvb6xPdpEncOH7UnAqhErJLLJ2fiiNmP7-6aU4x0-6BHsdiCUzVqv2YMtH4fw4Jo04RDuNdRQWw1hr_v9K_a606h-8xg2M4bu43_ysPGekfI1lQkgtX-GaFxfMsTCzPm6IXpFtg7M8i-Xlv06Ws4YRU7H8PY5UWqcZ5FElampPXVMR8eqUyJss6gj5vQdde8JrA4_fHs_5135Bm5TKWrurJC5LNDmiSqsFgrNIWXigyHc4rQwCt1EI4IJWVAmN0VmJjLPjEsxnOLgPIVBXEe_D8xPnFV54rUPqbBKGcxydDGxE5cXItNqBG97G5bnrUpHeaXHTONcEpONxrlMRyB6K5cdzGjhQ4lR5H_N9tEjSn2Ck2-5-jolaT5KCDGhHcG73sRlNwVUt3d0cKenn8F9elVLFH8Og3pz4V8gDqrNy87x6fppMV_SdXH0ffEHQFP8kg
link.rule.ids 315,783,787,24130,27938,27939,41095,42164,45693,52125
linkProvider Springer Nature
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV1Lb9NAEB7RVAg4AA2ghuceOPDQVk683rWPEaIE2uYAiVROq32iCnCq2D2UX89MvFYroEi9Wvba3hnPfOP99huAl67MSoN-wE0UBRfKem6cyrkxvnCTKGPsWL5zOVuKT8fFcdrH3fRs935JchOpLza7YWonxoTkpHLG8y3YFhNE-wPYnn74enDp14qoqE6htnIZdSLEDN2vZ_5rnKsy0lY0q7_WRzdpZ_8eLPoH7tgm3_fOWrvnfv2h5XjNN7oPdxMMZdPOb3bgRqiHcOeSOOEQbm7Ioa4Zwk4KAA17lVSqXz-A9ZShA4UfPK5DYKR9TY0CSO-fIR435wzRMPOh3VC9araKzPGjc8d-fp5PGeVOz_DwKZFqfGA1ySrTpe7EM1N71pwQZZvVpsaqPpH3HsJy__3i3YynBg7c5VK03DshS1mh1TNVOSMU2kPKLERLyMUbYRU6ikEME4uobGmrwo5lWVifY0LFyXkEg3pVh11gYeydKrNgQsyFU8pinWOqsRv7shKFUSN40xtRn3Y6HfpCkZnmWROXjeZZ5yMQvZl1AhodgNCYR_532S66hDbfMPzq5ZcJifNRSYgl7Qje9ibWKQg0Vw_0-Fpnv4Bbs8XRoT78OD94Arfpth1t_CkM2vVZeIaoqLXP01fwG1Nd_TU
linkToPdf http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1Nb9QwEB3RrUBwKHQBdaGADxz4kNukcezkuGpZCoUVAlYqJ-NPVAHZ1SY9lF_PzCZRK6BIiGsUO4ln4nljP78BeOyKpDDoB9xEkXOhrOfGqYwb43O3F2WMLct3Kg9n4vVxftzVOa17tnu_JdmeaSCVpqrZXfi4e37wDcM8sSckJ8Uznq3BukgRLQxgffzy09GFZRZRUs5CJeYSqkqI0brf2_xTP5dFp7Vo5r_tla5C0OQmfO5fvmWefN05beyO-_GLruN_fN0t2OjgKRu3_rQJV0I1hBsXRAuHcHVFGnX1EDa7iaFmTzr16qe3YTlm6FjhG4_LEBhpYlMBAaoDwBCnmzOGKJn50KwoYBWbR-b42zPHvr-fjhnFVM_w8oLINj6wiuSWqak78cxUntUnROVmlakw2-9IfXdgNnnxcf-Qd4UduMukaLh3QhayRG9IVOmMUGgbKZMQLSEab4RV6EAGsU3Mo7KFLXObyiK3PsNAi4NzFwbVvApbwELqnSqSYELMhFPKYv5jytSlvihFbtQInvUG1YtWv0OfKzXTOGviuNE462wEoje57gBICyw0xpe_NdtC99DmC07LevZhj0T7KFXEVHcEz3tz625yqC_v6N4_3f0Irr07mOg3r6ZH9-E6PbVlk2_DoFmehgcIlhr7sPshfgIL9AYo
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=A+label-free+colorimetric+assay+for+detection+of+c-Myc+mRNA+based+on+peptide+nucleic+acid+and+silver+nanoparticles&rft.jtitle=Science+bulletin+%28Beijing%29&rft.au=Li%2C+Xia&rft.au=Song%2C+Juan&rft.au=Chen%2C+Bao-Li&rft.au=Wang%2C+Bing&rft.date=2016-02-01&rft.pub=Science+China+Press&rft.issn=2095-9273&rft.eissn=2095-9281&rft.volume=61&rft.issue=4&rft.spage=276&rft.epage=281&rft_id=info:doi/10.1007%2Fs11434-016-1004-3&rft.externalDocID=10_1007_s11434_016_1004_3
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2095-9273&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2095-9273&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2095-9273&client=summon